ArticleTranslational vision science & technology2020
Correlation of Visual Field With Peripapillary Vessel Density Through Optical Coherence Tomography Angiography in Normal-Tension Glaucoma.
Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Peripapillary Vessel Density Mediates the Relationship Between Axial Length and Visual Field Damage in Glaucoma.Journal of clinical medicine · 2026Article
- A Comparison of Vessel Density in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma Patients Using OCT Angiography.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- A Comparison of Vessel Density in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma Patients Using OCT Angiography [Letter].Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Association of contrast sensitivity with vessel density and functional parameters in different stages of glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Detection and agreement of event-based OCT and OCTA analysis for glaucoma progression.Eye (London, England) · 2024Article
- Peripapillary Vascular Density in Compressive Optic Neuropathy and Normal-Tension Glaucoma: A Severity-Controlled Comparison.Investigative ophthalmology & visual science · 2023Article
- Optical Coherence Tomography Angiography (OCTA) Differences in Vessel Perfusion Density and Flux Index of the Optic Nerve and Peri-Papillary Area in Healthy, Glaucoma Suspect and Glaucomatous Eyes.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Neuroprotection in Glaucoma: Basic Aspects and Clinical Relevance.Journal of personalized medicine · 2022Review
- The Topographic Relationship Between Choroidal Microvascular Dropout and Glaucomatous Damage in Primary Angle-Closure Glaucoma.Translational vision science & technology · 2022Article
- A Global and Sector-Based Comparison of OCT Angiography and Visual Field Defects in Glaucoma.Journal of ophthalmology · 2022Article
- Exploring Ocular Perfusion and Structural Alterations of POAG in Indonesia: Insights from OCTA and OCT Analysis.Journal of current glaucoma practiceArticle
- Comparing optical coherence tomography angiography biomarker for primary open-angle glaucoma and normal tension glaucoma progression in different stage.Taiwan journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate the retinal vessel density (VD) in healthy and normal-tension glaucoma (NTG) eyes through optical coherence tomography angiography (OCTA) and to determine the correlation between VD and the retinal nerve fiber layer (RNFL) thickness and functional visual field (VF) defects for different locations. Methods: A total of 74 NTG eyes and 24 healthy eyes were included. OCTA VD at 4.5 × 4.5 mm peripapillary region and 3.0 × 3.0 mm macula area, RNFL thickness, and VF pattern deviation results were individually analyzed on the basis of the Garway-Heath sectorization. Correlations between VD and VF/RNFL and VF were compared. Results: In the NTG group, peripapillary VD, superficial macula VD, RNFL thickness, and ganglion cell complex thickness were significantly lower. In the whole peripapillary area and inferotemporal sector, anatomic correlations between VD and VF pattern deviation values were significantly higher than those between the RNFL thickness and VF values. In the subgroup analysis, VD was anatomically correlated with VF in early-, moderate-, and severe-stage NTG eyes, whereas the RNFL thickness was correlated with VF in moderate- and severe-stage NTG eyes. Conclusions: We observed VD reduction in the peripapillary retina and superficial macula area in NTG eyes. The microvascular dropout of VD in the peripapillary retina, especially in the inferotemporal sector, provided a more accurate anatomic correlation with functional VF defects than that of the RNFL thickness, especially in early-stage NTG eyes. Translational Relevance: In patients who cannot comply VF exam, VD is a good tool for disease detection.
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Registered trials
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