Evidence map›Paper›PMID 33363898›Full record

ArticleClinical case reports2020

Gynecomastia and hypertension in a patient treated with posaconazole.

George R Thompson, Prasanth N Surampudi, Alex Odermatt

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

George R ThompsonDepartment of Internal Medicine Division of Infectious Diseases University of California Davis Medical Center Davis CA USA.
Prasanth N SurampudiDepartment of Internal Medicine Division of Endocrinology University of California Davis Medical Center Davis CA USA.
Alex OdermattSwiss Centre for Applied Human Toxicology and Division of Molecular and Systems Toxicology Department of Pharmaceutical Sciences University of Basel Basel Switzerland.ORCID https://orcid.org/0000-0002-6820-2712
University of California Davis Medical Center · USUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posaconazole therapy may lead to increased serum estradiol levels and development of gynecomastia. Early detection by endocrine hormone measurements may help preventing gynecomastia.

Indexed as

11beta‐hydroxylaseadverse drug effectestradiolgynecomastiahypertensionhypokalemiaposaconazole

Identifiers

PMID33363898
PMCPMC7752548
OpenAlexW3090790488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.