Evidence map›Paper›PMID 33363781›Full record

ArticleClinical case reports2020

Trimethoprim-induced drug reaction with eosinophilia and systemic symptoms (DRESS) associated with reactivation of human herpes virus-6 (HHV-6) leading to acute liver failure.

Mohsan Subhani, Victor Dong, Aveen Connolly, Jonathan Salisbury, Rosa Miquel, Sarah Walsh, Tasneem Pirani

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mohsan SubhaniLiver Intensive Therapy Unit (LITU) King's College Hospital London UK.ORCID https://orcid.org/0000-0001-8739-7263
Victor DongLiver Intensive Therapy Unit (LITU) King's College Hospital London UK.ORCID https://orcid.org/0000-0002-6875-3768
Aveen ConnollyDepartment of Dermatology King's College Hospital London UK.ORCID https://orcid.org/0000-0002-3470-7405
Jonathan SalisburyDepartment of Histopathology King's College Hospital London UK.ORCID https://orcid.org/0000-0002-5889-4276
Rosa MiquelLiver Histopathology Laboratory King's College Hospital London UK.ORCID https://orcid.org/0000-0001-7414-0186
Sarah WalshDepartment of Dermatology King's College Hospital London UK.ORCID https://orcid.org/0000-0001-7251-9547
Tasneem PiraniLiver Intensive Therapy Unit (LITU) King's College Hospital London UK.ORCID https://orcid.org/0000-0001-7357-7634
King's College Hospital · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome can have insidious symptoms which may lead to acute liver failure and death. Prompt recognition, stopping offending drug, and initiating corticosteroid are the mainstay of treatment. Early involvement of a specialist liver unit is vital.

Indexed as

acute liver failuredrug‐induced liver injurydrug reaction with eosinophilia and systemic symptomshuman herpes virus‐6jaundiceliver transplant

Identifiers

PMID33363781
PMCPMC7752394
OpenAlexW3048775129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.