ArticleActa endocrinologica (Bucharest, Romania : 2005)
ATHEROGENIC INDICES IN THE ASSESSMENT OF CARDIOVASCULAR DISEASE RISK IN CHILDREN WITH OBESITY AND SUBCLINICAL HYPOTHYROIDISM.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 7 citations in OpenAlex.
- Consumption of Eggs Alone or Enriched with Annatto (Nutrients · 2023Trial
- Association of insulin-like growth factor 1 and metabolic parameters with mild subclinical hypothyroidism in obese boys.Scientific reports · 2025Article
- Isolated Hyperthyrotropinemia Adversely Influences Lipid Metabolism in Children and Adolescents with Obesity.Turkish archives of pediatrics · 2022Article
- Paeonol suppresses lipid formation and promotes lipid degradation in adipocytes.Experimental and therapeutic medicine · 2022Article
- Atherosclerosis Risk Factors in Patients with Reactive Hypoglycemia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Thyroid Function in Adults with Prader-Willi Syndrome; a Cohort Study and Literature Review.Journal of clinical medicine · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe frequency of subclinical hypothyroidism (SH) in patients with obesity is increased compared with the normal population. However, data on the risk of cardiovascular disease (CVD) in patients with SH are still scarce. Lipid parameters are strong predictors of early CVD. We aimed to investigate the role of lipid indices in predicting CVD risk compared to conventional lipid components.
methodsA total of 220 euthyroid obese children (EU) and 90 obese children with SH were included in the study. All data were collected from hospital files. Lipid indices were evaluated. Atherogenic index of plasma (AIP), cardiac risk ratio (CRR) and atherogenic coefficient (AC) were calculated. AIP>0.24, CRR>5 ve AC>3 were considered as cardiovascular risk criteria.
resultsThe presence of SH increased the risk of higher AIP and the risk of CRR, compared to euthyroid obese children.
conclusionSubclinical hypothyroidism in obese children may cause dislipidemia carrying a high cardiovascular disease risk.
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