Evidence map›Paper›PMID 33363633›Full record

ArticleAsian journal of pharmaceutical sciences2020

Enhancement in antinociceptive and anti-inflammatory effects of tramadol by transdermal proniosome gel.

Jigar Shah, Anroop B Nair, Hiral Shah, Shery Jacob, Tamer M Shehata, Mohamed Aly Morsy

Abstract read
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
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  5. Preparation,Pharmaceutical nanotechnology · 2025
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  9. Review
  10. Brucine Entrapped Titanium Oxide Nanoparticle for Anticancer Treatment: AnAdvances in pharmacological and pharmaceutical sciences · 2024
    Article
  11. Review
  12. Recent Progress in Gels for Neuropathic Pain.Gels (Basel, Switzerland) · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jigar ShahInstitute of Pharmacy, Nirma University, Ahmedabad 382481, India.
Anroop B NairCollege of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Hiral ShahArihant School of Pharmacy & BRI, Gandhinagar 382421, India.
Shery JacobCollege of Pharmacy, Gulf Medical University, Ajman 4184, United Arab Emirates.
Tamer M ShehataCollege of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Mohamed Aly MorsyCollege of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral therapy of tramadol, an opiate analgesic, undergoes extensive hepatic metabolism and requires frequent administration. Transdermal therapy by virtue can overcome these issues and can improve the efficacy and reduce abuse liability of tramadol. The aim of this research was to investigate the possibility of transdermal delivery of tramadol by formulating proniosome gel and evaluate its therapeutic potential

Indexed as

EdemaFluxPharmacokineticsProniosomesRatsTramadol

Identifiers

PMID33363633
PMCPMC7750831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.