ArticlePatient preference and adherence2020
Cross-Cultural Adaptation and Reliability Testing of Chinese Version of the Living with Medicines Questionnaire in Elderly Patients with Chronic Diseases.
Article in Patient preference and adherence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Analysis of Medication-Related Burden and Associated Factors Among Elderly Patients with Coronary Heart Disease: A Cross-Sectional Study.Patient preference and adherence · 2026Article
- The influence of medication burden on the quality of life among patients with breast cancer undergoing adjuvant endocrine therapy: The mediating role of medication beliefs.Asia-Pacific journal of oncology nursing · 2025Article
- Prevalence and influencing factors of medication-related burden among patients with late-life depression in typical city of eastern China: a cross-sectional study.BMC public health · 2024Article
- Evaluation of viral suppression and medication-related burden among HIV-infected adults in a secondary care facility.Exploratory research in clinical and social pharmacy · 2024Article
- Choice intention for the national volume-based procurement drug and its associated factors: a cross-sectional study on patients with late-life depression in China.BMC psychiatry · 2024Article
- Scoping review of measures of treatment burden in patients with multimorbidity: advancements and current gaps.Journal of clinical epidemiology · 2023Article
- Development and initial validation of the Chinese Version of the Noise Exposure Questionnaire (C-NEQ).BMC public health · 2022Article
- Polypharmacy, Medication-Related Burden and Antiretroviral Therapy Adherence in People Living with HIV Aged 50 and Above: A Cross-Sectional Study in Hunan, China.Patient preference and adherence · 2022Article
- Exploring polypharmacy burden among elderly patients with chronic diseases in Chinese community: a cross-sectional study.BMC geriatrics · 2021Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Living with Medicines Questionnaire (LMQ-3) is a reliable, valid instrument used to assess the medication-related burden of patients with chronic disease using long-term medication, but it has not been used in China. PURPOSE: To translate and cross-culturally adapt the LMQ-3 into Chinese and assess its reliability and validity among elderly patients with chronic disease.
methodsAfter translation and back-translation, views from an expert group and cognitive interviews with elderly persons using multiple medicines were used to ensure the cultural relevance of the LMQ-3. Then, 412 participants aged 60-92 years were recruited from three communities in Zhengzhou to complete the instrument. Item analysis, internal consistency, content validity, exploratory factor analysis (EFA) and reliability testing were performed.
resultsItem analysis identified nine items for possible removal, which were discussed with the originating team. Internal consistency testing confirmed the suitability of removing two of these items, which concurred with the views of the expert group and cognitive interviews. All other items were retained, but four were modified for clarification without changing their meaning, resulting in a 39-item instrument. EFA of this 39-item measure yielded an eight-factor model, similar to the English version. Cronbach's alpha of the Chinese version of LMQ-3 (C-LMQ-3) for elderly patients with chronic diseases was 0.855, and alpha values for the eight domains ranged from 0.822 to 0.932. Test-retest reliability was satisfactory, with ICC values for the eight domain scores ranging from 0.751 to 0.881.
conclusionWith only minor modifications compared to the English version, the 39-item C-LMQ-3 is a valid tool, with adequate reliability, which can be used to assess the medication-related burden of long-term use of multiple medicines in elderly patients in China.
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