Evidence map›Paper›PMID 33363263›Full record

ArticleKidney international reports2021

Systematic Review and Meta-analysis of COVID-19 and Kidney Transplant Recipients, the South West London Kidney Transplant Network Experience.

Mysore Phanish, Irina Chis Ster, Abbas Ghazanfar, Nicholas Cole, Virginia Quan, Richard Hull, Debasish Banerjee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Incidence and Outcomes of COVID-19 in People With CKD: A Systematic Review and Meta-analysis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2021
    Pooled it
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  7. Review
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  16. Humoral response to SARS-CoV-2 is well preserved and symptom dependent in kidney transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Observational
  17. Review
  18. Review
  19. SARS-CoV-2 vaccination in solid-organ transplant recipients: What the clinician needs to know.Transplant international : official journal of the European Society for Organ Transplantation · 2021
    Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mysore PhanishRenal Unit, St Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, London, UK.
Irina Chis SterInstitute of infection and immunity, St George's University of London, UK.
Abbas GhazanfarRenal and Transplantation Unit, St George's University Hospitals NHS Foundation Trust, London, UK.
Nicholas ColeRenal Unit, St Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, London, UK.
Virginia QuanRenal Unit, St Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, London, UK.
Richard HullRenal and Transplantation Unit, St George's University Hospitals NHS Foundation Trust, London, UK.
Debasish BanerjeeMolecular and Clinical Sciences Research Institute, St George's, University of London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is paucity of literature comparing outcomes of kidney transplant patients with COVID-19 to that of dialysis and waitlisted patients. This report describes our data, provides comparative analysis, together with a meta-analysis of published studies, and describes our protocols to restart the transplant program.

methodsData were analyzed on kidney transplant, dialysis, and waitlisted patients tested positive for SARS-CoV-2 (nasopharyngeal swab polymerase chain reaction [PCR] test) between March 1, 2020, and June 30, 2020, together with a meta-analysis of 16 studies.

resultsTwenty-three of 1494 kidney transplant patients tested positive for SARS-CoV-2 compared with 123 of 1278 hemodialysis patients (1.5% vs. 9.6%,

conclusionsFrom our cohort of transplant patients, a significantly lower proportion of patients contracted COVID-19 compared with waitlisted and dialysis patients. The case fatality ratio was comparable to that of the dialysis cohort and to a pooled case fatality ratio from a meta-analysis of 16 studies. The pooled AKI ratio in the meta-analysis was similar to our results.

Identifiers

PMID33363263
PMCPMC7748968

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.