Evidence map›Paper›PMID 33363190›Full record

ArticleFrontiers in medicine2020

Use of Venovenous Extracorporeal Membrane Oxygenation in Critically-Ill Patients With COVID-19.

Mathieu Jozwiak, Jean-Daniel Chiche, Julien Charpentier, Zakaria Ait Hamou, Paul Jaubert, Sarah Benghanem, Pierre Dupland, Ariane Gavaud, Frédéric Péne, Alain Cariou and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Mathieu JozwiakAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Jean-Daniel ChicheAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Julien CharpentierAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Zakaria Ait HamouAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Paul JaubertAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Sarah BenghanemAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Pierre DuplandAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Ariane GavaudAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Frédéric PéneAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Alain CariouAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Jean-Paul MiraAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Lee S NguyenAssistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Paris-Centre, Hôpital Cochin, Service de Médecine Intensive Réanimation, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRGroupe Hospitalier Cochin - Port-Royal, Hôtel-Dieu, Broca - La Collégiale · FRHôpital Cochin · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) related to Coronavirus disease (COVID-19) is associated with high mortality. It has been suggested that venovenous extracorporeal membrane oxygenation (ECMO) was suitable in this indication, albeit the effects of ECMO on the mechanical respiratory parameters have been scarcely described. In this case-series, we prospectively described the use of venovenous ECMO and its effects on mechanical respiratory parameters in eleven COVID-19 patients with severe ARDS. Implantation of ECMO occurred 6 [3-11] days after the onset of mechanical ventilation. At the time of ECMO implantation, all patients received neuromuscular blocking agents, three (27%) received inhaled nitric oxide and prone positioning was performed in all patients with 4 [3-5] sessions of PP per patient. Under ECMO, the tidal volume was significantly decreased from 6.1 [4.0-6.3] to 3.4 [2.5-3.6] mL/kg of predicted body weight and the positive end-expiratory pressure level was increased by 25 ± 27% whereas the driving pressure and the mechanical power decreased by 33 ± 25% and 71 ± 27%, respectively. The PaO

Indexed as

acute respiratory distress syndrome—ARDSCOVID-19extracorporeal membrane oxygenation (ECMO)intensive care unit (ICU)mechanical ventilation

Identifiers

PMID33363190
PMCPMC7758460
OpenAlexW3111328927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.