Evidence map›Paper›PMID 33363136›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Anti-glioblastoma Activity of Kaempferol via Programmed Cell Death Induction: Involvement of Autophagy and Pyroptosis.

Suqin Chen, Jing Ma, Liu Yang, Muzhou Teng, Zheng-Quan Lai, Xiaoyu Chen, Jingjin He

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
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  5. Correlative study ofFrontiers in microbiology · 2026
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  12. The Small Molecules of Plant Origin with Anti-Glioma Activity.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Suqin ChenThe Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Jing MaThe Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Liu YangThe Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Muzhou TengSchool of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zheng-Quan LaiDepartment of Pharmacy, Shenzhen University General Hospital, Shenzhen University, Shenzhen, China.
Xiaoyu ChenDepartment of Neurology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Jingjin HeThe Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Eighth Affiliated Hospital of Sun Yat-sen UniversitySun Yat-sen University · CNShenzhen University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma is one of the most common and lethal intracranial malignant, and is still lack of ideal treatments. Kaempferol is a major nutrient found in various edible plants, which has exhibited the potential for the treatment of glioblastoma. However, the specific anti-glioma mechanism of kaempferol is yet to be studied. Herein, we aim to explore the mechanisms underlying the anti-glioma activity of kaempferol. Our results demonstrated that kaempferol suppresses glioma cell proliferation

Indexed as

autophagyglioblastomakaempferolpyroptosisROS

Identifiers

PMID33363136
PMCPMC7758214
OpenAlexW3111489325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.