Evidence map›Paper›PMID 33363053›Full record

ReviewFrontiers in cellular and infection microbiology2020

Midgut Mitochondrial Function as a Gatekeeper for Malaria Parasite Infection and Development in the Mosquito Host.

Shirley Luckhart, Michael A Riehle

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  4. Evolution of innate immunity: lessons from mammalian models shaping our current view of insect immunity.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Review
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  7. bioRxiv : the preprint server for biology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Shirley LuckhartDepartment of Entomology, Plant Pathology and Nematology, University of Idaho, Moscow, ID, United States.
Michael A RiehleDepartment of Entomology, University of Arizona, Tucson, AZ, United States.
University of Arizona · USUniversity of Idaho · US

Funding

Systems biology approach to MAPK regulation of malaria infection in A. stephensiR01AI080799 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LUCKHART, SHIRLEY, VODOVOTZ, YORAM · 2009 to 2013
$3.4M
Insulin, IGF and Insulin Signaling: effects on Anopheles lifespan and immunityR01AI073745 · NIAID · UNIVERSITY OF ARIZONA · PI RIEHLE, MICHAEL ALLEN · 2008 to 2012
$2.5M
Plasmodium signaling of innate immunity in AnophelesR01AI060664 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI LUCKHART, SHIRLEY · 2004 to 2007
$940k
Harnessing midgut mitochondrial dynamics to enhance Anopheline mosquito fitnessR56AI107263 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LUCKHART, SHIRLEY, RIEHLE, MICHAEL ALLEN · 2014 to 2014
$775k
Midgut mitochondrial function as a driver of resistance and fitness in mosquitoesR56AI129420 · NIAID · UNIVERSITY OF ARIZONA · PI LUCKHART, SHIRLEY, RIEHLE, MICHAEL ALLEN · 2018 to 2018
$726k
Midgut mitochondria as the key to fit, Plasmodium-resistant Anopheline mosquitoesR56AI118926 · NIAID · UNIVERSITY OF IDAHO · PI GIULIVI, CECILIA, LUCKHART, SHIRLEY · 2016 to 2016
$707k
Improving Anopheline fitness and resistance through fat body insulin signalingR21AI125823 · NIAID · UNIVERSITY OF ARIZONA · PI RIEHLE, MICHAEL ALLEN · 2016 to 2017
$426k
NIAID NIH HHS R01 AI060664NIAID NIH HHS R01 AI073745NIAID NIH HHS R01 AI080799NIAID NIH HHS R21 AI125823NIAID NIH HHS R56 AI107263
6 · The paper itself

Abstract

Across diverse organisms, various physiologies are profoundly regulated by mitochondrial function, which is defined by mitochondrial fusion, biogenesis, oxidative phosphorylation (OXPHOS), and mitophagy. Based on our data and significant published studies from

Indexed as

AnophelesMalariaAnimalsDrosophila melanogasterHost-Parasite InteractionsMitochondriaMosquito VectorsAnophelesimmunitymalariamidgutmitochondriamosquitoPlasmodiumresistance

Identifiers

PMID33363053
PMCPMC7759495
OpenAlexW3112461954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.