Evidence map›Paper›PMID 33363041›Full record

ReviewFrontiers in oncology2020

MR-Guided Radiotherapy for Prostate Cancer.

Boris R Tocco, Amar U Kishan, Ting Martin Ma, Linda G W Kerkmeijer, Alison C Tree

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Boris R ToccoDepartment of Radiotherapy, The Royal Marsden NHS Foundation Trust, London, United Kingdom.
Amar U KishanUniversity of California, Los Angeles, Los Angeles, CA, United States.
Ting Martin MaUniversity of California, Los Angeles, Los Angeles, CA, United States.
Linda G W KerkmeijerRadboud University Medical Center, Nijmegen, Netherlands.
Alison C TreeDepartment of Radiotherapy, The Royal Marsden NHS Foundation Trust, London, United Kingdom.

Funding

Cancer Research UK 28284
6 · The paper itself

Abstract

External beam radiotherapy remains the primary treatment modality for localized prostate cancer. The radiobiology of prostate carcinoma lends itself to hypofractionation, with recent studies showing good outcomes with shorter treatment schedules. However, the ability to accurately deliver hypofractionated treatment is limited by current image-guided techniques. Magnetic resonance imaging is the main diagnostic tool for localized prostate cancer and its use in the therapeutic setting offers anatomical information to improve organ delineation. MR-guided radiotherapy, with daily re-planning, has shown early promise in the accurate delivery of radiotherapy. In this article, we discuss the shortcomings of current image-guidance strategies and the potential benefits and limitations of MR-guided treatment for prostate cancer. We also recount present experiences of MR-linac workflow and the opportunities afforded by this technology.

Indexed as

image-guided radiotherapyMR-guided radiotherapyMR-linaconline adaptive radiotherapyprostate cancer

Identifiers

PMID33363041
PMCPMC7757637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.