Evidence map›Paper›PMID 33363009›Full record

ArticleFrontiers in oncology2020

Systemic Inflammation Response Index Is a Predictor of Poor Survival in Locally Advanced Nasopharyngeal Carcinoma: A Propensity Score Matching Study.

Yuhua Feng, Na Zhang, Sisi Wang, Wen Zou, Yan He, Jin-An Ma, Ping Liu, Xianling Liu, Chunhong Hu, Tao Hou

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In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  15. Prognostic value of pretreatment peripheral blood hemoglobin×lymphocyte/monocyte ratio in patients with nasopharyngeal carcinoma.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuhua FengDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Na ZhangDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Sisi WangDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Wen ZouDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Yan HeDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Jin-An MaDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Ping LiuDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Xianling LiuDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Chunhong HuDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.
Tao HouDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNasopharyngeal carcinoma (NPC) is a common malignancy in China and known prognostic factors are limited. In this study, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune inflammation index (SII), and systemic inflammation response index (SIRI) were evaluated as prognostic factors in locally advanced NPC patients. MATERIALS AND

methodsNPC patients who received curative radiation or chemoradiation between January 2012 and December 2015 at the Second Xiangya Hospital were retrospectively reviewed, and a total of 516 patients were shortlisted. After propensity score matching (PSM), 417 patients were eventually enrolled. Laboratory and clinical data were collected from the patients' records. Receiver operating characteristic curve analysis was used to determine the optimal cut-off value. Survival curves were analyzed using the Kaplan-Meier method. The Cox proportional hazard model was used to identify prognostic variables.

resultsAfter PSM, all basic characteristics between patients in the high SIRI group and low SIRI group were balanced except for sex (

conclusionOur findings indicate that SIRI might be a promising predictive indicator of locally advanced NPC patients.

Indexed as

locally advancednasopharyngeal carcinomaprognosissurvivalsystemic inflammation response index

Identifiers

PMID33363009
PMCPMC7759154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.