Evidence map›Paper›PMID 33362916›Full record

ReviewWorld journal of radiology2020

Clinical features and radiological manifestations of COVID-19 disease.

Pedro Landete, Carlos Andrés Quezada Loaiza, Beatriz Aldave-Orzaiz, Susana Hernández Muñiz, Antonio Maldonado, Enrique Zamora, Allan Charles Sam Cerna, Elia Del Cerro, Raquel Cano Alonso, Felipe Couñago

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Investigation of phytochemicals isolated from selected Saudi medicinal plants as natural inhibitors of SARS CoV-2 main protease: In vitroSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. COVID-19 inflammation and implications in drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Review
  10. Review
  11. Aspirin in COVID-19: Pros and Cons.Frontiers in pharmacology · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Review
  17. Review
  18. Review
  19. Article
  20. Hypoxia may be a determinative factor in COVID-19 progression.Current research in pharmacology and drug discovery · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Pedro LandeteDepartment of Pulmonology, H. U. La Princesa, Madrid 28006, Spain.
Carlos Andrés Quezada LoaizaDepartment of P ulmonology, H. 12 de Octubre, Madrid 28041, Spain.
Beatriz Aldave-OrzaizDepartment of Pulmonology, H. U. La Princesa, Madrid 28006, Spain.
Susana Hernández MuñizDepartment of Radiologist, H. U. La Princesa, Madrid 28006, Spain.
Antonio MaldonadoDepartment of Nuclear Medicine, Hospital Universitario Quironsalud Madrid, Madrid 28223, Spain.
Enrique ZamoraDepartment of Pulmonology, H. U. La Princesa, Madrid 28006, Spain.
Allan Charles Sam CernaDepartment of Pulmonology, Hospital MD Anderson Madrid. España, Madrid 28033, Spain.
Elia Del CerroDepartment of Radiation Oncology, Hospital Universitario Quirónsalud Madrid, Pozuelo de Alarcón, Madrid 28223, Spain.
Raquel Cano AlonsoDepartment of Diagnostic Imaging, Hospital Universitario Quirón Madrid, Madrid 28223, Spain.
Felipe CouñagoDepartment of Radiation Oncology, Hospital Universitario Quirónsalud Madrid, Pozuelo de Alarcón, Madrid 28223, Spain.
Hospital Universitario de La Princesa · ESHospital Universitario Quirónsalud Madrid · ESMD Anderson Cancer Center Madrid · ESResearch Institute Hospital 12 de Octubre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) was discovered after unusual cases of severe pneumonia emerged in December 2019 in Wuhan Province (China). Coronavirus is a family of single-stranded RNA viruses. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted from person to person. Although asymptomatic individuals can transmit the virus, symptomatic patients are more contagious. The incubation period ranges from 3-7 d and symptoms are mainly respiratory, including pneumonia or pulmonary embolism in severe cases. Elevated serum levels of interleukins (IL)-2, IL-6, IL-7 indicate the presence of cytokine release syndrome, which is associated with disease severity. The disease has three main phases: Viral infection, pulmonary involvement, and hyperinflammation. To date, no treatment has proved to be safe or effective. Chest X-ray and computed tomography (CT) are the primary imaging tests for diagnosis of SARS-CoV-2 pneumonia, follow-up, and detection of complications. The main radiological findings are ground-glass opacification and areas of consolidation. The long-term clinical course is unknown, although some patients may develop pulmonary fibrosis. Positron emission tomography-computed tomography (PET-CT) is useful to assess pulmonary involvement, to define the affected areas, and to assess treatment response. The pathophysiology and clinical course of COVID-19 infection remain poorly understood. However, patterns detected on CT and PET-CT may help to diagnose and guide treatment. In this mini review, we analyze the clinical manifestations and radiological findings of COVID-19 infection.

Indexed as

Clinical featuresCoronavirusCOVID-19Natural historyPathogenesisRadiology images

Identifiers

PMID33362916
PMCPMC7745468
OpenAlexW3110139450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.