Evidence map›Paper›PMID 33362772›Full record

ArticleFrontiers in immunology2020

Resistance to Experimental Visceral Leishmaniasis in Mice Infected With

Manuel Soto, Laura Ramírez, José Carlos Solana, Emma C L Cook, Elena Hernández-García, Sara Charro-Zanca, Ana Redondo-Urzainqui, Rosa M Reguera, Rafael Balaña-Fouce, Salvador Iborra

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Manuel SotoCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Departamento de Biología Molecular, Nicolás Cabrera 1, Universidad Autónoma de Madrid, Madrid, Spain.
Laura RamírezCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Departamento de Biología Molecular, Nicolás Cabrera 1, Universidad Autónoma de Madrid, Madrid, Spain.
José Carlos SolanaCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Departamento de Biología Molecular, Nicolás Cabrera 1, Universidad Autónoma de Madrid, Madrid, Spain.
Emma C L CookDepartment of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Elena Hernández-GarcíaDepartment of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Sara Charro-ZancaDepartment of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Ana Redondo-UrzainquiDepartment of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Rosa M RegueraDepartamento de Ciencias Biomédicas, Universidad de León, León, Spain.
Rafael Balaña-FouceDepartamento de Ciencias Biomédicas, Universidad de León, León, Spain.
Salvador IborraDepartment of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Universidad Complutense de Madrid · ESCentro de Biología Molecular Severo Ochoa · ESUniversidad de León · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unveiling the protective immune response to visceral leishmaniasis is critical for a rational design of vaccines aimed at reducing the impact caused by this fatal, if left untreated, vector-borne disease. In this study we sought to determine the role of the basic leucine zipper transcription factor ATF-like 3 (Batf3) in the evolution of infection with

Indexed as

Leishmania infantumAnimalsBasic-Leucine Zipper Transcription FactorsBone MarrowCytokinesDisease Models, AnimalDisease ResistanceFemaleLeishmaniasis, VisceralLiverMice, Inbred C57BLMice, KnockoutNitritesRepressor ProteinsSpleenT-LymphocytesBasic-Leucine Zipper Transcription FactorsCytokinesNitritesRepressor ProteinsSNFT protein, mouseBatf3Batf3 DC+dendritic cellsLeishmaniaTh1 responsesvisceral leishmaniasis

Identifiers

PMID33362772
PMCPMC7758202
OpenAlexW3112951190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.