Evidence map›Paper›PMID 33362559›Full record

ArticleFrontiers in pharmacology2020

Vitamin D Attenuates Ischemia/Reperfusion-Induced Cardiac Injury by Reducing Mitochondrial Fission and Mitophagy.

Tzu-Lin Lee, Ming-Hsueh Lee, Yu-Chen Chen, Yi-Chieh Lee, Tsai-Chun Lai, Hugo You-Hsien Lin, Lee-Fen Hsu, Hsin-Ching Sung, Chiang-Wen Lee, Yuh-Lien Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
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  5. Mitophagy in cardiovascular diseases: a literature review.Cardiovascular diagnosis and therapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tzu-Lin LeeDepartment of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Ming-Hsueh LeeDivision of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Yu-Chen ChenDepartment of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yi-Chieh LeeDepartment of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Tsai-Chun LaiDepartment of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hugo You-Hsien LinDivision of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Lee-Fen HsuDivision of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Hsin-Ching SungDepartment of Anatomy, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chiang-Wen LeeDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Chiayi, Taiwan.
Yuh-Lien ChenDepartment of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
National Taiwan University · TWChang Gung University of Science and Technology · TWKaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction is the leading cause of morbidity and mortality worldwide. Although myocardial reperfusion after ischemia (I/R) is an effective method to save ischemic myocardium, it can cause adverse reactions, including increased oxidative stress and cardiomyocyte apoptosis. Mitochondrial fission and mitophagy are essential factors for mitochondrial quality control, but whether they play key roles in cardiac I/R injury remains unknown. New pharmacological or molecular interventions to alleviate reperfusion injury are currently considered desirable therapies. Vitamin D

Indexed as

apoptosiscardiac ischemia/reperfusionmitochondrial fissionmitophagyvitamin D3

Identifiers

PMID33362559
PMCPMC7758530
OpenAlexW3111508783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.