Evidence map›Paper›PMID 33362549›Full record

ArticleFrontiers in pharmacology2020

Complementary Chinese Herbal Medicine Therapy Improves Survival in Patients With Pemphigus: A Retrospective Study From a Taiwan-Based Registry.

Po-Yuan Wu, Te-Mao Li, Shu-I Chen, Chao-Jung Chen, Jian-Shiun Chiou, Ming-Kuem Lin, Fuu-Jen Tsai, Yang-Chang Wu, Ting-Hsu Lin, Chiu-Chu Liao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Po-Yuan WuDepartment of Dermatology, China Medical University Hospital, Taichung, Taiwan.
Te-Mao LiSchool of Chinese Medicine, China Medical University, Taichung, Taiwan.
Shu-I ChenDepartment of Chinese Medicine, Asia University Hospital, Taichung, Taiwan.
Chao-Jung ChenProteomics Core Laboratory, Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Jian-Shiun ChiouDepartment of Health Services Administration, China Medical University, Taichung, Taiwan.
Ming-Kuem LinDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung, Taiwan.
Fuu-Jen TsaiSchool of Chinese Medicine, China Medical University, Taichung, Taiwan.
Yang-Chang WuSchool of Chinese Medicine, China Medical University, Taichung, Taiwan.
Ting-Hsu LinProteomics Core Laboratory, Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Chiu-Chu LiaoProteomics Core Laboratory, Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Shao-Mei HuangProteomics Core Laboratory, Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Yu-Ning LinProteomics Core Laboratory, Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Wen-Miin LiangDepartment of Health Services Administration, China Medical University, Taichung, Taiwan.
Ying-Ju LinSchool of Chinese Medicine, China Medical University, Taichung, Taiwan.
China Medical University · TWAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pemphigus is a life-threatening and skin-specific inflammatory autoimmune disease, characterized by intraepidermal blistering between the mucous membranes and skin. Chinese herbal medicine (CHM) has been used as an adjunct therapy for treating many diseases, including pemphigus. However, there are still limited studies in effects of CHM treatment in pemphigus, especially in Taiwan. To more comprehensively explore the effect of long-term CHM treatment on the overall mortality of pemphigus patients, we performed a retrospective analysis of 1,037 pemphigus patients identified from the Registry for Catastrophic Illness Patients database in Taiwan. Among them, 229 and 177 patients were defined as CHM users and non-users, respectively. CHM users were young, predominantly female, and had a lesser Charlson comorbidity index (CCI) than non-CHM users. After adjusting for age, sex, prednisolone use, and CCI, CHM users had a lower overall mortality risk than non-CHM users (multivariate model: hazard ratio (HR): 0.422, 95% confidence interval (CI): 0.242-0.735,

Indexed as

association rule miningChinese herbal medicinenetworkoverall mortalitypemphigus

Identifiers

PMID33362549
PMCPMC7756119
OpenAlexW3110651308

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.