Evidence map›Paper›PMID 33362472›Full record

ArticleFrontiers in cellular neuroscience2020

Synaptic Vesicles Dynamics in Neocortical Epilepsy.

Eleonora Vannini, Laura Restani, Marialaura Dilillo, Liam A McDonnell, Matteo Caleo, Vincenzo Marra

Open access · greenAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Microscale Neuronal Activity Collectively Drives Chaotic and Inflexible Dynamics at the Macroscale in Seizures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Eleonora VanniniNeuroscience Institute, National Research Council (CNR), Pisa, Italy.
Laura RestaniNeuroscience Institute, National Research Council (CNR), Pisa, Italy.
Marialaura DililloFondazione Pisana per la Scienza Onlus (FPS), Pisa, Italy.
Liam A McDonnellFondazione Pisana per la Scienza Onlus (FPS), Pisa, Italy.
Matteo CaleoNeuroscience Institute, National Research Council (CNR), Pisa, Italy.
Vincenzo MarraDepartment of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, United Kingdom.
Fondazione Pisa · ITUniversity of Leicester · GBNational Academies of Sciences, Engineering, and Medicine · USUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuronal hyperexcitability often results from an unbalance between excitatory and inhibitory neurotransmission, but the synaptic alterations leading to enhanced seizure propensity are only partly understood. Taking advantage of a mouse model of neocortical epilepsy, we used a combination of photoconversion and electron microscopy to assess changes in synaptic vesicles pools

Indexed as

epilepsyhyperexcitabilitysynaptic vesiclestetanus neurotoxinvisual cortexvisual processing

Identifiers

PMID33362472
PMCPMC7758433
OpenAlexW2998690636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.