ArticleFrontiers in molecular neuroscience2020
Abnormal Levels of Metal Micronutrients and Autism Spectrum Disorder: A Perspective Review.
Article in Frontiers in molecular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 33 citations in OpenAlex.
- Iron dysregulation in the central nervous system: implications for autism spectrum disorder.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Review
- Elemental and Isotopic Profiles in Blood and Urine of Jordanian Children with Autism Spectrum Disorder: a Preliminary Comparative Study with Neurotypical Children.Biological trace element research · 2026Article
- Prenatal valproic acid exposure alters striatal proteomic signatures associated with autism spectrum disorder in mice.Translational psychiatry · 2026Article
- Copper deficiency impairs oligodendrocyte maturation and social behavior via mitophagy and mTOR suppression in ASD.Science advances · 2026Article
- Co-exposure to lead and cadmium is associated with increased severity of social deficits in children with autism spectrum disorders.Frontiers in nutrition · 2026Article
- Elucidating Biological Links in Autism Spectrum Disorder: From Blood-Based Risk Factor Identification to a Validated Nomogram for Early Risk Stratification.Neuropsychiatric disease and treatment · 2026Article
- An impaired glycolysis induces ATP deficiency and reduced cell respiration in stem cells of patients with autism spectrum disorders.Scientific reports · 2025Article
- Metallomic Profiling of Autism Spectrum Disorder in Sarajevo Canton, Bosnia and Herzegovina: Insights from Hair Sample Analysis.Biological trace element research · 2025Article
- Assessment of Essential and Toxic Element Levels in the Toenails of Children with Autism Spectrum Disorder.Biological trace element research · 2025Article
- Gamma-aminobutyric acid and glutamate system dysregulation in a small population of Egyptian children with autism spectrum disorder.Metabolic brain disease · 2025Article
- The Effects of Fisetin and Curcumin on Oxidative Damage Caused by Transition Metals in Neurodegenerative Diseases.Molecular neurobiology · 2025Review
- Association of metallic elements with telomere length in children with autism spectrum disorder.PeerJ · 2025Article
- Central Causation of Autism/ASDs via Excessive [CaBrain sciences · 2024Review
- Mercury and Autism Spectrum Disorder: Exploring the Link through Comprehensive Review and Meta-Analysis.Biomedicines · 2023Review
- Mineral elements and adiposity-related consequences in adolescents with intellectual disabilities.BMC molecular and cell biology · 2023Observational
- Review
- Plasma zinc, copper and serum ceruloplasmin levels of autism spectrum disorder children in Bangladesh.Heliyon · 2023Article
- Microbiome-Gut-Mucosal-Immune-Brain Axis and Autism Spectrum Disorder (ASD): A Novel Proposal of the Role of the Gut Microbiome in ASD Aetiology.Behavioral sciences (Basel, Switzerland) · 2023Review
- Hair Trace Elements and Mineral Content in Moroccan Children with Autism Spectrum Disorder: a Case-Control Study.Biological trace element research · 2023Article
- Active Sulfate-Reducing Bacterial Community in the Camel Gut.Microorganisms · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present review is to summarize the prevalence of abnormal levels of various metal micronutrients including copper (Cu), iron (Fe), magnesium (Mg), zinc (Zn), and selenium (Se) in Autism Spectrum Disorder (ASD) using hair, nail and serum samples. A correlation of selected abnormal metal ions with known neurodevelopmental processes using Gene Ontology (GO) term was also conducted. Data included in this review are derived from ASD clinical studies performed globally. Metal ion disparity data is also analyzed and discussed based on gender (Male/Female) to establish any gender dependent correlation. Finally, a rational perspective and possible path to better understand the role of metal micronutrients in ASD is suggested.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.