ArticleWorld journal of gastroenterology2020
Value of shear wave elastography with maximal elasticity in differentiating benign and malignant solid focal liver lesions.
Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 14 citations in OpenAlex.
- Accuracy of shear wave elastography in diagnosing axillary lymph node metastasis in patients with suspicious axillary lymph nodes: development of a predictive nomogram.Journal of ultrasound · 2025Article
- Liver Elastography Methods for Diagnosis of De Novo and Recurrent Hepatocellular Carcinoma.Diagnostics (Basel, Switzerland) · 2025Review
- Linking elastographic evaluation benign and malignant liver lesion with histopathological data.Bioinformation · 2025Article
- Multiparametric Dynamic Ultrasound Approach for Differential Diagnosis of Primary Liver Tumors.International journal of molecular sciences · 2023Article
- Article
- Advances in the clinical application of ultrasound elastography in uterine imaging.Insights into imaging · 2022Review
- Differential diagnosis of different types of solid focal liver lesions using two-dimensional shear wave elastography.World journal of gastroenterology · 2022Article
- An investigation of the efficacy of shear wave elastography in the characterization of benign and malignant liver lesions.Polish journal of radiology · 2022Article
- Is There a Place for Elastography in the Diagnosis of Hepatocellular Carcinoma?Journal of clinical medicine · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is important to differentiate benign and malignant focal liver lesions (FLLs) accurately. Despite the wide use and acceptance of shear wave elastography (SWE), its value for assessing the elasticity of FLLs and differentiating benign and malignant FLLs is still investigational. Previous studies of SWE for FLLs used mean elasticity as the parameter to reflect the stiffness of FLLs. Considering the inhomogeneity of tumor stiffness, maximal elasticity (Emax) might be the suitable parameter to reflect the stiffness of FLLs and to differentiate malignant FLLs from benign ones.
aimTo explore the value of SWE with Emax in differential diagnosis of solid FLLs.
methodsWe included 104 solid FLLs in 95 patients and 50 healthy volunteers. All the subjects were examined using conventional ultrasound (US) and virtual touch tissue quantification(VTQ) imaging. A diagnosis of benign or malignant FLL was made using conventional US. Ten VTQ values were acquired after 10 consecutive measurements for each FLL and each normal liver, and the largest value was recorded as Emax.
resultsThere were 56 cases of malignant FLLs and 48 cases of benign FLLs in this study. Emax of malignant FLLs (3.29 ± 0.88 m/s) was significantly higher than that of benign FLLs (1.30 ± 0.46 m/s,
conclusionSWE is a convenient and easy method to obtain accurate stiffness information of solid FLLs. Emax is useful for differential diagnosis of FLLs, especially in combination with conventional US.
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