ArticleWorld journal of gastroenterology2020
Liver fibrosis index-based nomograms for identifying esophageal varices in patients with chronic hepatitis B related cirrhosis.
Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 6 citations in OpenAlex.
- Direct venous-to-arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report.Experimental and therapeutic medicine · 2026Article
- Development and validation of a nomogram for predicting advanced liver fibrosis in patients with chronic hepatitis B.Frontiers in molecular biosciences · 2024Article
- Nomogram model for predicting early onset of chronic kidney disease using color Doppler region of interest technique.Abdominal radiology (New York) · 2022Article
- Double-Negative T Cells Regulate Hepatic Stellate Cell Activation to Promote Liver Fibrosis ProgressionFrontiers in immunology · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundEsophageal varices (EV) are the most fatal complication of chronic hepatitis B (CHB) related cirrhosis. The prognosis is poor, especially after the first upper gastrointestinal hemorrhage.
aimTo construct nomograms to predict the risk and severity of EV in patients with CHB related cirrhosis.
methodsBetween 2016 and 2018, the patients with CHB related cirrhosis were recruited and divided into a training or validation cohort at The First Affiliated Hospital of Wenzhou Medical University. Clinical and ultrasonic parameters that were closely related to EV risk and severity were screened out by univariate and multivariate logistic regression analyses, and integrated into two nomograms, respectively. Both nomograms were internally and externally validated by calibration, concordance index (C-index), receiver operating characteristic curve, and decision curve analyses (DCA).
resultsA total of 307 patients with CHB related cirrhosis were recruited. The independent risk factors for EV included Child-Pugh class [odds ratio (OR) = 7.705, 95% confidence interval (CI) = 2.169-27.370,
conclusionNomograms incorporating clinical and ultrasonic variables are efficient in noninvasively predicting the risk and severity of EV.
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