Evidence map›Paper›PMID 33362372›Full record

ArticleWorld journal of gastroenterology2020

Discovery of unique African

Takaaki Ono, Modesto Cruz, Hiroyuki Nagashima, Phawinee Subsomwong, Junko Akada, Takashi Matsumoto, Tomohisa Uchida, Rumiko Suzuki, Celso Hosking, José A Jiménez Abreu and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Gastric cancer burden and regional disparities among Helicobacter pylori-positive patients in the Americas: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Takaaki OnoDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.
Modesto CruzInstitute of Microbiology and Parasitology, IMPA, Faculty of Science, Autonomous University of Santo Domingo, Santo Domingo 10103, Dominican Republic.
Hiroyuki NagashimaDepartment of Gastroenterology, Hokkaido Cancer Center, Sapporo 003-0804, Japan.
Phawinee SubsomwongDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.
Junko AkadaDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.
Takashi MatsumotoDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.
Tomohisa UchidaDepartment of Molecular Pathology, Oita University Faculty of Medicine, Yufu 879-5593, Japan.
Rumiko SuzukiDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.
Celso HoskingInstitute of Microbiology and Parasitology, IMPA, Faculty of Science, Autonomous University of Santo Domingo, Santo Domingo 10103, Dominican Republic.
José A Jiménez AbreuDominican-Japanese Digestive Disease Center, Dr Luis E. Aybar Health and Hygiene City, Santo Domingo 10302, Dominican Republic.
Yoshio YamaokaDepartment of Environmental and Preventive Medicine, Oita University Faculty of Medicine, Yufu 879-5593, Japan.
Oita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

aimTo better understand the EPIYA patterns and CM motifs of the

methodsGastric mucosal biopsy specimens were obtained from 258 patients with dyspepsia living in the Dominican Republic, from which 120

resultsAll

conclusionWe found the unique African CM motif in Western-type CagA and termed it Africa1-CM. The less toxicity of this motif could be one reason to explain the African enigma.

Indexed as

Helicobacter InfectionsHelicobacter pyloriAfricaAmino Acid MotifsAntigens, BacterialBacterial ProteinsDominican RepublicHumansMultilocus Sequence TypingAntigens, BacterialBacterial ProteinsCagACagA 3' regionCagA-multimerization motifDominican RepublicGlu-Pro-Ile-Tyr-Ala motifHelicobacter pylori

Identifiers

PMID33362372
PMCPMC7723664
OpenAlexW3112202377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.