Evidence map›Paper›PMID 33361799›Full record

ArticleThe Journal of antibiotics2021

Salicylaldehyde derivatives from a marine-derived fungus Eurotium sp. SCSIO F452.

Weimao Zhong, Yuchan Chen, Xiaoyi Wei, Junfeng Wang, Weimin Zhang, Fazuo Wang, Si Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in The Journal of antibiotics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Secondary Metabolites from the GenusFoods (Basel, Switzerland) · 2023
    Review
  2. Secondary Metabolites Produced by the Blue-Cheese Ripening MoldJournal of fungi (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Weimao ZhongCAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, 510301, Guangzhou, China.
Yuchan ChenState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangdong Institute of Microbiology, 100 Central Xianlie Road, 510070, Guangzhou, China.
Xiaoyi WeiKey Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, 510650, Guangzhou, China.ORCID http://orcid.org/0000-0002-4053-6999
Junfeng WangCAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, 510301, Guangzhou, China.ORCID http://orcid.org/0000-0001-6702-5366
Weimin ZhangState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangdong Institute of Microbiology, 100 Central Xianlie Road, 510070, Guangzhou, China.
Fazuo WangCAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, 510301, Guangzhou, China. wangfazuo@scsio.ac.cn.
Si ZhangCAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, 510301, Guangzhou, China. zhsimd@scsio.ac.cn.
Chinese Academy of Sciences · CNGuangdong Academy of Sciences · CNBeijing Botanical Garden · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two pairs of new salicylaldehyde derivative enantiomers, salicylaldehydiums A and B (1 and 2), along with five known analogues were isolated and identified from a marine-derived fungus Eurotium sp. SCSIO F452. Their structures and absolute configuration were determined by extensive spectroscopic analysis and electronic circular dichroism (ECD) calculations. All the new optical pure enantiomers [(+)-1, (-)-1, (+)-2, (-)-2] were evaluated for their cytotoxic and antioxidative activities. Compound (-)-1 exhibited weak cytotoxic activity.

Indexed as

AldehydesAntioxidantsAquatic OrganismsCircular DichroismDrug Evaluation, PreclinicalEurotiumHep G2 CellsHumansMagnetic Resonance SpectroscopyMolecular StructureSpectrometry, Mass, Electrospray IonizationStereoisomerismAldehydesAntioxidantssalicylaldehyde

Identifiers

PMID33361799
OpenAlexW3116160832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.