Evidence map›Paper›PMID 33361696›Full record

ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre2021

Preoperative Controlling Nutritional Status plus Tumor Burden Score for the Assessment of Prognosis after Curative Liver Resection for Hepatocellular Carcinoma.

Yasuyuki Fukami, Takuya Saito, Takaaki Osawa, Takashi Arikawa, Tatsuki Matsumura, Shintaro Kurahashi, Shunichiro Komatsu, Kenitiro Kaneko, Tsuyoshi Sano

Open access · diamondAbstract read
In one paragraph

Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. [The value of the nutritional assessment index or score in prognostic evaluation for patients with liver cancer].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yasuyuki FukamiDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan, yasuyuki490225@yahoo.co.jp.
Takuya SaitoDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan.
Takaaki OsawaDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan.
Takashi ArikawaDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan.
Tatsuki MatsumuraDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan.
Shintaro KurahashiDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan.
Shunichiro KomatsuDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan.
Kenitiro KanekoDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan.
Tsuyoshi SanoDivision of Gastroenterological Surgery, Department of Surgery, Aichi Medical University, Nagakute, Japan.
Aichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere are no previous studies analyzing the prognostic predictive value of adding the tumor factor (i.e., Tumor Burden (TB) score) to the Controlling Nutritional Status (CONUT) score for patients with hepatocellular carcinoma (HCC). This study aimed to investigate the value of the CONUT plus TB (CONUT-TB) score as a prognostic predictor in patients with HCC undergoing liver resection.

methodsBetween 2015 and 2018, 96 consecutive patients with HCC underwent liver resection at our institution. Patients undergoing repeated liver resection and combined resection of a metastatic lesion were excluded. Patients were divided into 2 groups according to their CONUT-TB scores according to a cutoff value. Clinicopathologic prognostic factors for survival were analyzed using a database containing the medical records.

resultsThe optimal cutoff value of the CONUT-TB score determined by using a minimum p value approach was 13 points. Among the 81 patients included in the analytic cohort, 71 patients had low (<13) and 10 patients had high (>13) CONUT-TB scores. The overall 3-year survival rate of patients following liver resection for HCC in the high-CONUT-TB group was significantly worse than that of patients in the low-CONUT-TB group (62.5 vs. 89.3%, p = 0.003). Multivariate analysis indicated that a high CONUT-TB score was independently associated with overall survival after liver resection (p = 0.010).

conclusionThe CONUT-TB score is a valuable predictor of survival in patients with HCC after liver resection.

Indexed as

Nutritional StatusSeverity of Illness IndexTumor BurdenAdultAgedAged, 80 and overCarcinoma, HepatocellularFemaleHepatectomyHumansLiver NeoplasmsMaleMiddle AgedPerioperative CarePrognosisRetrospective StudiesControlling Nutritional Status scoreHepatocellular carcinomaLiver resectionPrognostic factorTumor burden score

Identifiers

PMID33361696
PMCPMC8114066
OpenAlexW3114472795

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.