ReviewJournal of biosciences2020
Vasopressin in circadian function of SCN.
Review in Journal of biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- The dual role of arginine vasopressin in immune regulation: Balancing immunostimulation and immunosuppression.Brain, behavior, & immunity - health · 2026Review
- Expression of gastrointestinal clock genes and associated hormones levels in hibernating and non-hibernating Daurian ground squirrels.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026Article
- Mapping the Connection Between Circadian Rhythms, Metabolism, and Neurodegeneration: Exploring Therapeutic Strategies.Current Alzheimer research · 2025Review
- Hepatocellular Carcinoma in Mice Affects Neuronal Activity and Glia Cells in the Suprachiasmatic Nucleus.Biomedicines · 2024Article
- Arginine vasopressin in mood disorders: A potential biomarker of disease pathology and a target for pharmacologic intervention.Psychiatry and clinical neurosciences · 2024Review
- Neuronal reprogramming of mouse and human fibroblasts using transcription factors involved in suprachiasmatic nucleus development.iScience · 2024Article
- Circadian Regulation of Apolipoproteins in the Brain: Implications in Lipid Metabolism and Disease.International journal of molecular sciences · 2023Review
- Vasopressin as Possible Treatment Option in Autism Spectrum Disorder.Biomedicines · 2023Review
- Vasopressin as a Possible Link between Sleep-Disturbances and Memory Problems.International journal of molecular sciences · 2022Review
- Identification of the suprachiasmatic nucleus venous portal system in the mammalian brain.Nature communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The suprachiasmatic nucleus (SCN) that acts as the primary circadian pacemaker in mammals is responsible for orchestrating multiple circadian rhythms in every organism. A network structure in the SCN composed of multiple types of neurons orchestrates the circadian rhythms. Despite speculations regarding the working of the clock, the molecular mechanisms governing it is far from clear. The molecular mechanism seems to be woven around the genes present and their linking with the neuromodulators. With the advancement in knowledge regarding the role of neuromodulators in the workings of the clock, especially that of Arginine vasopressin (AVP) and vasoactive intestinal peptide (VIP), the entire picture of the mechanisms involved and therefore the importance of these neuromodulators has changed considerably. AVP seems to be very important for the functioning of the clock and its role has been well established based on the evidence available at present. Enormous research is going on to study the role of AVP and new roles are likely to be assigned to AVP in the execution of function in the SCN. Of late, there have been reports indicating linkage of AVP with jet lag in a positive way, suggesting vasopressin signalling as a possible remedy for ill effects and their improvement. Studies also show circadian rhythm disturbances in mood disorders and the same is related to AVP levels in the SCN. Various findings are thus in accordance with strong suggestions for a critical role for AVP in SCN function.
Indexed as
Identifiers
33361631W3095927486What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.