ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Hippocampus Guides Adaptive Learning during Dynamic Social Interactions.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed, 43 citations in OpenAlex.
- Cortical thickness in perirhinal area BA35 predicts adaptive episodic memory-guided decision making in older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Individual differences in prosocial learning are represented in the hippocampal dorsal CA1.Nature neuroscience · 2026Article
- Compressed sensing-based approach identifies modular neural circuitry driving learned pathogen avoidance.eLife · 2026Article
- MRI study on hippocampal subfield volume loss and abnormal functional connectivity in patients with diabetic retinopathy.BMC medical imaging · 2025Article
- Social versus nonsocial visual cues of trustworthiness uniquely influence trust related behavior and memory.Scientific reports · 2025Article
- Age-related differences in trust decisions: when memory fails and appearances prevail.Social cognitive and affective neuroscience · 2025Article
- Learned phenotypes emerge during social stress modifying hippocampal orexin receptor gene expression.Scientific reports · 2024Article
- [A study on the effects of learning on the properties of rats hippocampal-prefrontal connections in a memory task].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Article
- Disrupted brain functional asymmetry at rest in patients with major depressive disorder associated with sleep disturbances.Brain imaging and behavior · 2024Article
- Learning, Fast and Slow: Single- and Many-Shot Learning in the Hippocampus.Annual review of neuroscience · 2024Review
- Get out of my head: social evaluative brain states carry over into post-feedback rest and influence remembering how others view us.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Novel Social Stimulation Ameliorates Memory Deficit in Alzheimer's Disease Model through Activating α-Secretase.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Integrated gut microbiome and metabolomic analyses elucidate the therapeutic mechanisms of Suanzaoren decoction in insomnia and depression models.Frontiers in neuroscience · 2024Article
- Neurocognitive Model of Schema-Congruent and -Incongruent Learning in Clinical Disorders: Application to Social Anxiety and Beyond.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- Cerebellum and hippocampus abnormalities in patients with insomnia comorbid depression: a study on cerebral blood perfusion and functional connectivity.Frontiers in neuroscience · 2023Article
- Social withdrawal and anxiety-like behavior have an impact on zebrafish adult neurogenesis.Frontiers in behavioral neuroscience · 2023Article
- Aging is associated with maladaptive episodic memory-guided social decision-making.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Transforming social perspectives with cognitive maps.Social cognitive and affective neuroscience · 2022Article
- The power of negative and positive episodic memories.Cognitive, affective & behavioral neuroscience · 2022Review
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
How do we evaluate whether someone will make a good friend or collaborative peer? A hallmark of human cognition is the ability to make adaptive decisions based on information garnered from limited prior experiences. Using an interactive social task measuring adaptive choice (deciding who to reengage or avoid) in male and female participants, we find the hippocampus supports value-based social choices following single-shot learning. These adaptive choices elicited a suppression signal in the hippocampus, revealing sensitivity for the subjective perception of a person and how well they treat you during choice. The extent to which the hippocampus was suppressed was associated with flexibly interacting with prior generous individuals and avoiding selfish individuals. Further, we found that hippocampal signals during decision-making were related to subsequent memory for a person and the offer they made before. Consistent with the hippocampus leveraging previously executed choices to solidify a reliable neural signature for future adaptive behavior, we also observed a later hippocampal enhancement. These findings highlight the hippocampus playing a multifaceted role in socially adaptive learning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.