Evidence map›Paper›PMID 33361425›Full record

ArticleJournal of virology2021

Plasmacytoid Dendritic Cells Mediate Control of Ross River Virus Infection via a Type I Interferon-Dependent, MAVS-Independent Mechanism.

Kelsey C Haist, Kathryn S Carpentier, Bennett J Davenport, Thomas E Morrison

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kelsey C HaistDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Kathryn S CarpentierDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Bennett J DavenportDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Thomas E MorrisonDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA thomas.morrison@cuanschutz.edu.ORCID 0000-0002-1811-2938
University of Colorado Denver · US

Funding

TRAINING PROGRAM IN IMMUNOLOGYT32AI007405 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Laurel L Lenz, Raul Martin Torres · 1991 to 2026
$10.5M
Impairment of B cell Responses by Pathogenic Chikungunya VirusesR01AI141436 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DIAMOND, MICHAEL S, MORRISON, THOMAS E · 2019 to 2023
$3.2M
Molecular Pathogenesis of Infectious DiseasesT32AI052066 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAN DYK, LINDA F. · 2002 to 2022
$2.3M
Mechanisms of immune suppression during arthritogenic alphavirus infectionsR01AI108725 · NIAID · UNIVERSITY OF COLORADO DENVER · PI MORRISON, THOMAS E · 2014 to 2018
$1.9M
Viral and Host Determinants of Chikungunya Virus DisseminationF32AI140567 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CARPENTIER, KATHRYN SEMMENS · 2018 to 2021
$170k
Mechanisms of monocyte-mediated control of alphavirus infectionF31AI122517 · NIAID · UNIVERSITY OF COLORADO DENVER · PI HAIST, KELSEY C · 2016 to 2017
$62k
NIAID NIH HHS F31 AI122517NIAID NIH HHS F32 AI140567NIAID NIH HHS R01 AI108725NIAID NIH HHS R01 AI141436NIAID NIH HHS T32 AI007405NIAID NIH HHS T32 AI052066
6 · The paper itself

Abstract

Ross River virus (RRV) is a mosquito-borne alphavirus that causes epidemics of debilitating musculoskeletal disease. To define the innate immune mechanisms that mediate control of RRV infection, we studied a RRV strain encoding 6 nonsynonymous mutations in nsP1 (RRV-T48-nsP1

Indexed as

Adaptor Proteins, Signal TransducingAlphavirus InfectionsAnimalsAntiviral AgentsDendritic CellsImmunity, InnateInterferon Type IMiceMutationRoss River virusSignal TransductionViral LoadViral Nonstructural ProteinsVirulenceAdaptor Proteins, Signal TransducingAntiviral AgentsInterferon Type IMAVS protein, mouseViral Nonstructural ProteinsalphavirusinterferonMAVSpDCs

Identifiers

PMID33361425
PMCPMC8094935
OpenAlexW3115501173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.