ArticleAJNR. American journal of neuroradiology2021
Regional Aneurysm Wall Enhancement is Affected by Local Hemodynamics: A 7T MRI Study.
Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The association between hemodynamics and wall characteristics in human intracranial aneurysms: a review.Neurosurgical review · 2022Pooled it
- Intracranial aneurysm wall enhancement as an indicator of instability: a systematic review and meta-analysis.European journal of neurology · 2021Pooled it
- Local pressure as a dominant hemodynamic driver of wall enhancement in anterior communicating artery aneurysms: a facet-level computational fluid dynamics and vessel wall imaging analysis.Quantitative imaging in medicine and surgery · 2026Article
- From hemodynamic stress to inflammatory wall remodeling in intracranial aneurysms.Frontiers in molecular biosciences · 2026Review
- Separate aneurysmal neck is essential for analyzing hemodynamics and predicting instability of intracranial aneurysms.Annals of medicine · 2025Article
- Comprehensive morphomechanical and wall enhancement analysis of intracranial aneurysms.European radiology · 2025Article
- Article
- Computational fluid dynamics-based virtual angiograms for the detection of flow stagnation in intracranial aneurysms.International journal for numerical methods in biomedical engineering · 2023Article
- Understanding development of jugular bulb stenosis in vein of galen malformations: identifying metrics of complex flow dynamics in the cerebral venous vasculature of infants.Frontiers in physiology · 2023Article
- Aneurysm wall enhancement, hemodynamics, and morphology of intracranial fusiform aneurysms.Frontiers in aging neuroscience · 2023Article
- Wall enhancement predictive of abnormal hemodynamics and ischemia in vertebrobasilar non-saccular aneurysms: a pilot study.Frontiers in neurology · 2023Article
- Brain Aneurysm Biology: What Can We Learn From Imaging?Stroke (Hoboken, N.J.) · 2022Article
- Aneurysmal wall enhancement and hemodynamics: pixel-level correlation between spatial distribution.Quantitative imaging in medicine and surgery · 2022Article
- Increased aneurysm wall permeability colocalized with low wall shear stress in unruptured saccular intracranial aneurysm.Journal of neurology · 2022Article
- Hemodynamic Characteristic Analysis of Aneurysm Wall Enhancement in Unruptured Middle Cerebral Artery Aneurysm.Frontiers in neurology · 2022Article
- Aneurysm risk metrics and hemodynamics are associated with greater vessel wall enhancement in intracranial aneurysms.Royal Society open science · 2021Article
- Luminal enhancement in intracranial aneurysms: fact or feature?-A quantitative multimodal flow analysis.International journal of computer assisted radiology and surgery · 2021Article
- Current Clinical Applications of Intracranial Vessel Wall MR Imaging.Seminars in ultrasound, CT, and MR · 2021Review
- Semiautomated 3D mapping of aneurysmal wall enhancement with 7T-MRI.Scientific reports · 2021Article
- Imaging Inflammation - From Whole Body Imaging to Cellular Resolution.Frontiers in immunology · 2021Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
background and purposeAneurysm wall enhancement has been proposed as a biomarker for inflammation and instability. However, the mechanisms of aneurysm wall enhancement remain unclear. We used 7T MR imaging to determine the effect of flow in different regions of the wall. MATERIALS AND
methodsTwenty-three intracranial aneurysms imaged with 7T MR imaging and 3D angiography were studied with computational fluid dynamics. Local flow conditions were compared between aneurysm wall enhancement and nonenhanced regions. Aneurysm wall enhancement regions were subdivided according to their location on the aneurysm and relative to the inflow and were further compared.
resultsOn average, wall shear stress was lower in enhanced than in nonenhanced regions (
conclusionsAneurysm wall enhancement regions tend to have lower wall shear stress than nonenhanced regions of the same aneurysm. Moreover, the association between flow conditions and aneurysm wall enhancement seems to depend on the location of the region on the aneurysm sac. Regions at the neck and close to the inflow tend to be exposed to higher wall shear stress and wall shear stress gradients. Regions at the body, dome, or far from the inflow tend to be exposed to uniformly low wall shear stress and have more aneurysm wall enhancement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.