Evidence map›Paper›PMID 33361336›Full record

ArticleJournal for immunotherapy of cancer2020

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lymphoma.

Sattva S Neelapu, Sherry Adkins, Stephen M Ansell, Joshua Brody, Mitchell S Cairo, Jonathan W Friedberg, Justin P Kline, Ronald Levy, David L Porter, Koen van Besien and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  13. Complement system in Anti-CD20 mAb therapy for cancer: A mini-review.International journal of immunopathology and pharmacology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Sattva S NeelapuDepartment of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Sherry AdkinsDepartment of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Stephen M AnsellDivision of Hematology, Department of Internal Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota, USA.
Joshua BrodyHematology and Oncology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Mitchell S CairoDepartment of Pediatrics, Medicine, Pathology, Microbiology and Immunology and Cell Biology, New York Medical College At Maria Fareri Children's Hospital, New York City, New York, USA.ORCID 0000-0002-2075-434X
Jonathan W FriedbergDepartment of Medicine, Hematology-Oncology Division, Wilmot Cancer Institute University of Rochester Medical Center, Rochester, New York, USA.
Justin P KlineDepartment of Medicine Section of Hematology/Oncology, University of Chicago, Chicago, Illinois, USA.
Ronald LevyDivision of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
David L PorterCell Therapy and Transplant and Division of Hematology Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Koen van BesienDivision of Hematology/Oncology, Weill Cornell Medical College, New York City, New York, USA.
Michael WernerFounder and CEO of HomeX, Chicago, Illinois, USA.
Michael R BishopDepartment of Medicine Section of Hematology/Oncology, University of Chicago, Chicago, Illinois, USA mbishop@medicine.bsd.uchicago.edu.
The University of Texas MD Anderson Cancer Center · USUniversity of Chicago · USCancer Institute (WIA) · INCornell University · USMaria Fareri Children's Hospital · USMayo Clinic · USPalmetto Hematology Oncology · USStanford University · USUPMC Hillman Cancer Center · US

Funding

Enhancing Cancer Immunotherapy: Targeting the Tumor and Targeting the HostR35CA197353 · NCI · STANFORD UNIVERSITY · PI LEVY, RONALD · 2016 to 2022
$6.1M
NCI NIH HHS R35 CA197353
6 · The paper itself

Abstract

The recent development and clinical implementation of novel immunotherapies for the treatment of Hodgkin and non-Hodgkin lymphoma have improved patient outcomes across subgroups. The rapid introduction of immunotherapeutic agents into the clinic, however, has presented significant questions regarding optimal treatment scheduling around existing chemotherapy/radiation options, as well as a need for improved understanding of how to properly manage patients and recognize toxicities. To address these challenges, the Society for Immunotherapy of Cancer (SITC) convened a panel of experts in lymphoma to develop a clinical practice guideline for the education of healthcare professionals on various aspects of immunotherapeutic treatment. The panel discussed subjects including treatment scheduling, immune-related adverse events (irAEs), and the integration of immunotherapy and stem cell transplant to form recommendations to guide healthcare professionals treating patients with lymphoma.

Indexed as

FemaleGuidelines as TopicHumansImmunotherapyLymphomaMaleantineoplastic protocolsguidelines as topichematologic neoplasmsimmunotherapy

Identifiers

PMID33361336
PMCPMC7768967
OpenAlexW3115312619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.