Evidence map›Paper›PMID 33361311›Full record

ArticleAntimicrobial agents and chemotherapy2021

Radicicol, a Novel Lead Compound against the Migratory-Stage Schistosomula of

Liangxiong Xu, Qiuli Liu, Qingren Zeng, Ping Wu, Quan Yu, Kongzhen Gu, Jinghua Xue, Xiaoyi Wei

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Liangxiong XuKey Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, People's Republic of China.ORCID 0000-0003-0389-8568
Qiuli LiuDepartment of Parasitolgy, Xiangya School of Medicine, Central South University, Changsha, People's Republic of China.
Qingren ZengDepartment of Parasitolgy, Xiangya School of Medicine, Central South University, Changsha, People's Republic of China zengqingren@csu.edu.cn wxy@scbg.ac.cn.ORCID 0000-0001-6352-3448
Ping WuKey Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, People's Republic of China.
Quan YuDepartment of Parasitolgy, Xiangya School of Medicine, Central South University, Changsha, People's Republic of China.
Kongzhen GuDepartment of Parasitolgy, Xiangya School of Medicine, Central South University, Changsha, People's Republic of China.
Jinghua XueKey Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, People's Republic of China.
Xiaoyi WeiKey Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, People's Republic of China zengqingren@csu.edu.cn wxy@scbg.ac.cn.
Central South University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schistosomiasis poses a serious threat to human health and remains a major tropical and parasitic disease in more than 70 countries. Praziquantel (PZQ) has been the primary treatment for schistosomiasis for nearly 4 decades. However, its efficacy against migratory-stage schistosomula is limited. Radicicol (RAD), a β-resorcylic acid lactone derived from

Indexed as

Schistosoma japonicumSchistosomicidesAnimalsHumansLeadMacrolidesPraziquantelSchistosoma mansoniLeadMacrolidesmonordenPraziquantelSchistosomicidesmigratory-stage schistosomularadicicolSchistosoma japonicumschistosomicidal efficacy

Identifiers

PMID33361311
PMCPMC8092499
OpenAlexW3117749821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.