Evidence map›Paper›PMID 33361202›Full record

ArticleInfection and immunity2021

Sphingolipid-Containing Outer Membrane Vesicles Serve as a Delivery Vehicle To Limit Macrophage Immune Response to Porphyromonas gingivalis.

Fernanda G Rocha, Gregory Ottenberg, Zavier G Eure, Mary E Davey, Frank C Gibson

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Infection and immunity · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Deciphering macrophage molecular responses toFrontiers in microbiology · 2026
    Article
  7. Sphingolipid-mediated vesiculation in multidrug-resistantApplied and environmental microbiology · 2025
    Article
  8. Human gut commensalGut microbes · 2025
    Article
  9. Article
  10. Article
  11. Journal of oral microbiology · 2025
    Article
  12. CRISPRJournal of oral microbiology · 2025
    Article
  13. Outer membrane vesicles ofFrontiers in microbiology · 2025
    Review
  14. Review
  15. Oral Pathobiont-Derived Outer Membrane Vesicles in the Oral-Gut Axis.International journal of molecular sciences · 2024
    Review
  16. Inhibition of SARS-CoV-2 infection byMicrobiology spectrum · 2024
    Article
  17. Review
  18. An outer membrane vesicle specific lipoprotein promotesCurrent research in microbial sciences · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fernanda G RochaDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Gregory OttenbergDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Zavier G EureDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Mary E DaveyDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA mdavey@dental.ufl.edu fgibson@dental.ufl.edu.ORCID 0000-0001-8129-0537
Frank C GibsonDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA mdavey@dental.ufl.edu fgibson@dental.ufl.edu.ORCID 0000-0003-1988-1170
University of Florida · US

Funding

Regulatory Mechanisms Controlling Expression of P. gingivalis Surface StructuresR01DE019117 · NIDCR · UNIVERSITY OF FLORIDA · PI DAVEY, MARY ELLEN · 2009 to 2019
$4.5M
L-Arg Availability Affects the Physiological State of Porphyromonas gingivalisR01DE024580 · NIDCR · UNIVERSITY OF FLORIDA · PI DAVEY, MARY ELLEN · 2015 to 2024
$3.5M
NIDCR NIH HHS R01 DE019117NIDCR NIH HHS R01 DE024580
6 · The paper itself

Abstract

Sphingolipids (SLs) are essential structural components of mammalian cell membranes. Our group recently determined that the oral anaerobe

Indexed as

Bacteroidaceae InfectionsBiological TransportHost-Pathogen InteractionsImmunomodulationMacrophagesMutationPorphyromonas gingivalisProteomicsSphingolipidsTransport VesiclesSphingolipidshost-pathogen interactionsouter membrane vesiclesperiodontitisPorphyromonas gingivalissphingolipids

Identifiers

PMID33361202
PMCPMC8090959
OpenAlexW3116047515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.