SynthesisBMJ open2020
Accuracy of continuous glucose monitoring in preterm infants: a systematic review and meta-analysis.
Synthesis in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Acute effects of exercise snacks on postprandial glucose and insulin metabolism in adults with obesity: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Efficacy and safety of electrical acupoint stimulation for postoperative nausea and vomiting: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants.The Cochrane database of systematic reviews · 2021Pooled it
- Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants.The Cochrane database of systematic reviews · 2020Pooled it
- Glucose disturbances in very low birth weight infants nearing term age-results from the prospective LIGHT-study using continuous glucose monitoring.European journal of pediatrics · 2025Observational
- Microwave Antenna Sensing for Glucose Monitoring in a Vein Model Mimicking Human Physiology.Biosensors · 2025Article
- Neonatal Hypoglycemia and Neurodevelopmental Outcomes-An Updated Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2024Review
- Accuracy to detect neonatal hyperglycaemia using real-time continuous glucose monitoring during postoperative period.European journal of pediatrics · 2023Article
- Glucose variability in 6-12-month-old healthy infants.Frontiers in nutrition · 2023Article
- Should continuous glucose monitoring be used to manage neonates at risk of hypoglycaemia?Frontiers in pediatrics · 2023Review
- Recent Developments and Future Perspective on Electrochemical Glucose Sensors Based on 2D Materials.Biosensors · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesContinuous glucose monitoring (CGM) could be a valuable instrument for measurement of glucose concentration in preterm neonate. We undertook a systematic review and meta-analysis to compare the diagnostic accuracy of CGM devices to intermittent blood glucose evaluation methods for the detection of hypoglycaemic or hypoglycaemic events in preterm infants. DATA SOURCES: A structured electronic database search was performed for studies that assessed the accuracy of CGM against any intermittent blood glucose testing methods in detecting episodes of altered glycaemia in preterm infants. No restrictions were used. Three review authors screened records and included studies. DATA EXTRACTION: Risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. From individual patient data (IPD), sensitivity and specificity were determined using predefined thresholds. The mean absolute relative difference (MARD) of the studied CGM devices was assessed and if those satisfied the accuracy requirements (EN ISO 15197). IPD datasets were meta-analysed using a logistic mixed-effects model. A bivariate model was used to estimate the summary
resultsAmong 4481 records, 11 were included. IPD datasets were obtained for five studies. Only two of the studies showed an MARD lower than 10%, with none of the five CGM devices studied satisfying the European Union (EU) ISO 15197 requirements. Pooled sensitivity and specificity of CGM devices for hypoglycaemia were 0.39 and 0.99, whereas for hyperglycaemia were 0.87 and 0.99, respectively. The AUC was 0.70 and 0.86, respectively. The certainty of the evidence was considered as low to moderate. Limitations primarily related to the lack of representative population, reference standard and CGM device.
conclusionsCGM devices demonstrated low sensitivity for detecting hypoglycaemia in preterm infants, however, provided high accuracy for detection of hyperglycaemia. PROSPERO REGISTRATION NUMBER: CRD42020152248.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.