Evidence map›Paper›PMID 33360669›Full record

ReviewCancer treatment and research communications2021

Cancer patients and COVID-19: Mortality, serious complications, biomarkers, and ways forward.

Kush Gupta, Shipra Gandhi, Alexander Mebane, Angelica Singh, Nivetha Vishnuvardhan, Eshan Patel

Abstract readReview
In one paragraph

Review in Cancer treatment and research communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Observational
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  11. Cancer Patients during COVID-19 Pandemic: A Mini-Review.Healthcare (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kush GuptaKasturba Medical College, Light House Hill Road, Mangalore, KA 575001, India. Electronic address: drkushgupta@gmail.com.
Shipra GandhiRoswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA. Electronic address: shipra.gandhi@roswellpark.org.
Alexander MebaneHeart, Vascular & Leg Center, 5020 Commerce Dr, Bakersfield, CA, 93309, USA. Electronic address: almurphysme@gmail.com.
Angelica SinghNewYork-Presbyterian/Brooklyn Methodist Hospital, 506 6th Street, Brooklyn, New York, 11215 USA. Electronic address: ans9289@nyp.org.
Nivetha VishnuvardhanNewYork-Presbyterian/Brooklyn Methodist Hospital, 506 6th Street, Brooklyn, New York, 11215 USA. Electronic address: niv9051@nyp.org.
Eshan PatelNewYork-Presbyterian/Brooklyn Methodist Hospital, 506 6th Street, Brooklyn, New York, 11215 USA. Electronic address: pateleshan@yahoo.com.

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Institutional Career DevelopmentKL2TR001413 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI DUBOCOVICH, MARGARITA L · 2015 to 2024
$4.2M
NCATS NIH HHS KL2 TR001413NCATS NIH HHS UL1 TR001412
6 · The paper itself

Abstract

The SARS-CoV-2 (COVID-19) pandemic has particularly serious consequences for cancer patients, as they are at high risk for severe complications and mortality due to the virus since cancer patients are immunocompromised. Preliminary evidence suggests that patients with hematological, and metastatic malignancies are particularly susceptible to developing severe COVID-19 illness, which leads to poor prognosis. Biomarkers including C-reactive protein and interleukin-6 may be predictors of outcome and, therefore, crucial in assessing COVID-19 illness severity in cancer patients. A patient-specific risk and benefit inventory should be completed, and expert guidelines consulted when deciding to continue or postpone therapeutic interventions. This review presents preliminary evidence of COVID-19 infection and its impact on cancer, as well as discussion of general guidelines for the treatment and management of cancer patients with COVID-19.

Indexed as

BiomarkersCOVID-19HumansNeoplasmsRisk FactorsBiomarkersBiomarkersCovid-19C-reactive proteinInterleukin-6Sever acute respiratory syndrome coronavirus 2

Identifiers

PMID33360669
PMCPMC7832265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.