Evidence map›Paper›PMID 33360440›Full record

ArticleJournal of psychiatric research2021

Hoarding disorder is associated with self-reported cardiovascular / metabolic dysfunction, chronic pain, and sleep apnea.

Sara K Nutley, Monica R Camacho, Joseph Eichenbaum, Rachel L Nosheny, Michael Weiner, Kevin L Delucchi, R Scott Mackin, Carol A Mathews

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Relationship of Hoarding and Depression Symptoms in Older Adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Article
  5. Brain health registry updates: An online longitudinal neuroscience platform.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sara K NutleyUniversity of Florida, Department of Epidemiology, 2004 Mowry Road, Gainesville, FL, 32610, USA. Electronic address: snutley@ufl.edu.
Monica R CamachoSan Francisco VA Medical Center, 4150 Clement St, San Francisco, CA, 94121, USA. Electronic address: monica.camacho@va.gov.
Joseph EichenbaumSan Francisco VA Medical Center, 4150 Clement St, San Francisco, CA, 94121, USA; University of California, San Francisco, Department of Radiology, 505 Parnassus Ave, San Francisco, CA, 94143, USA. Electronic address: joseph.eichenbaum@ucsf.edu.
Rachel L NoshenySan Francisco VA Medical Center, 4150 Clement St, San Francisco, CA, 94121, USA; University of California, San Francisco, Department of Psychiatry, 401 Parnassus Ave, San Francisco, CA, 94143, USA. Electronic address: rachel.nosheny@ucsf.edu.
Michael WeinerSan Francisco VA Medical Center, 4150 Clement St, San Francisco, CA, 94121, USA; University of California, San Francisco, Department of Radiology, 505 Parnassus Ave, San Francisco, CA, 94143, USA; University of California, San Francisco, Department of Psychiatry, 401 Parnassus Ave, San Francisco, CA, 94143, USA. Electronic address: michael.weiner@ucsf.edu.
Kevin L DelucchiUniversity of California, San Francisco, Department of Psychiatry, 401 Parnassus Ave, San Francisco, CA, 94143, USA. Electronic address: kevin.delucchi@ucsf.edu.
R Scott MackinSan Francisco VA Medical Center, 4150 Clement St, San Francisco, CA, 94121, USA; University of California, San Francisco, Department of Psychiatry, 401 Parnassus Ave, San Francisco, CA, 94143, USA. Electronic address: Scott.Mackin@ucsf.edu.
Carol A MathewsUniversity of Florida, Department of Psychiatry, 100 Newell Dr, Gainesville, FL, 32610, USA. Electronic address: carolmathews@ufl.edu.
San Francisco VA Medical Center · USUniversity of Florida · USUniversity of California, San Francisco · US

Funding

Predicting populations at-risk of developing pathological hoardingR01MH117114 · NIMH · UNIVERSITY OF FLORIDA · PI MACKIN, ROBERT SCOTT, MATHEWS, CAROL A · 2018 to 2022
$3.7M
The Brain Health Registry for facilitating interdisciplinary aging researchR33AG062867 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NOSHENY, RACHEL LAUREN · 2020 to 2024
$3.2M
Identifying Intermediate Phenotypes for Compulsive HoardingR21MH087748 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATHEWS, CAROL A · 2010 to 2011
$435k
NIA NIH HHS R33 AG062867NIMH NIH HHS R01 MH117114NIMH NIH HHS R21 MH087748
6 · The paper itself

Abstract

Hoarding behaviors are positively associated with medical morbidity, however, current prevalence estimates and types of medical conditions associated with hoarding vary. This analysis aims to quantify the medical morbidity of hoarding disorder (HD). Cross-sectional data were collected online using the Brain Health Registry (BHR). Among 20,745 participants who completed the Hoarding and Clutter and Medical History thematic modules, 1348 had HD (6.5%), 1268 had subclinical HD (6.1%), and 18,829 did not meet hoarding criteria (87.4%). Individuals with HD were more likely to report a lifetime history of cardiovascular/metabolic conditions: diabetes (HD adjusted odds ratio (AOR):1.51, 95% confidence interval (CI):[1.20, 1.91]; subclinical HD AOR:1.24, 95% CI:[0.95, 1.61]), and hypercholesterolemia (HD AOR:1.24, 95% CI:[1.06, 1.46]; subclinical HD AOR:1.11, 95% CI:[0.94, 1.31]). Those with HD and subclinical HD were also more to report chronic pain (HD AOR: 1.69, 95% CI:[1.44, 1.98]; subclinical HD AOR: 1.44, 95% CI:[1.22, 1.69]), and sleep apnea (HD AOR: 1.58, 95% CI:[1.31, 1.89]; subclinical HD AOR:1.30, 95% CI:[1.07, 1.58]) than non-HD participants. For most conditions, likelihood of diagnosis did not differ between HD and subclinical HD. Structural equation modeling revealed that more severe hoarding symptomatology was independently associated with increased cardiovascular/metabolic vulnerability. The assessment and management of medical complications in individuals with HD is a fundamental component in improving quality of life, longevity, and overall physical health outcomes.

Indexed as

Chronic PainHoarding DisorderSleep Apnea SyndromesCross-Sectional StudiesHumansQuality of LifeSelf ReportCardiovascular healthChronic painHoardingHoarding disorderMedical comorbiditySleep

Identifiers

PMID33360440
PMCPMC8108138
OpenAlexW3111843547

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.