Evidence map›Paper›PMID 33360376›Full record

ReviewMolecular immunology2021

Reading the room: iNKT cells influence B cell responses.

Elizabeth A Leadbetter, Mikael C I Karlsson

Open access · greenAbstract readReview
In one paragraph

Review in Molecular immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Elizabeth A LeadbetterDepartment of Microbiology, Immunology & Molecular Genetics, UT Health San Antonio, TX, USA. Electronic address: leadbetter@uthscsa.edu.
Mikael C I KarlssonDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden. Electronic address: mikael.karlsson@ki.se.
Karolinska Institutet · SEThe University of Texas Health Science Center at San Antonio · US

Funding

Innate modulation of autoimmune, regulatory, and effector B cells in adipose tissueR01AI132798 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LEADBETTER, ELIZABETH ANN · 2018 to 2022
$1.9M
NIAID NIH HHS R01 AI132798
6 · The paper itself

Abstract

Rapid immune responses regulated by invariant Natural Killer T (iNKT) cells bridge the gap between innate and adaptive responses to pathogens, while also providing key regulation to maintain immune homeostasis. iNKT immune protection and immune regulation are both mediated through interactions with innate and adaptive B cell populations that express CD1d. Recent studies have expanded our understanding of the position of iNKT cells at the fulcrum between regulating inflammatory and autoreactive B cells. Environmental signals influence iNKT cells to set the tone for subsequent adaptive responses, ranging from maintaining homeostasis as an iNKT regulatory cell (iNKT

Indexed as

Lymphocyte ActivationAnimalsAutoimmunityB-LymphocytesHumansImmunity, InnateInflammationNatural Killer T-CellsB(reg) cells(FH)iNKT(reg)Humoral immunityiNKTinvariant Natural Killer T cells (iNKT)Marginal zone B cells

Identifiers

PMID33360376
PMCPMC7927200
OpenAlexW3113455369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.