Evidence map›Paper›PMID 33360242›Full record

ArticleForensic science international2021

Persistence of SARS-CoV-2 RNA in post-mortem swab 35 days after death: A case report.

Pasquale Beltempo, Serena Maria Curti, Renato Maserati, Mirella Gherardi, Maurizio Castelli

Abstract readCase Reports
In one paragraph

Article in Forensic science international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Post-mortem persistence of SARS-CoV-2: a preliminary study.Forensic science, medicine, and pathology · 2021
    Article
  15. Article
  16. Fire and fear: Rapid cremations in the Philippines amidst COVID-19.Forensic science international. Synergy · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pasquale BeltempoS.C. Medicina Legale, Azienda USL Valle d'Aosta, Località Amerique 7/L, 11020, Quart (AO), Italy. Electronic address: pbeltempo@ausl.vda.it.
Serena Maria CurtiS.C. Medicina Legale, Azienda USL Valle d'Aosta, Località Amerique 7/L, 11020, Quart (AO), Italy. Electronic address: scurti@ausl.vda.it.
Renato MaseratiDipartimento Scienze mediche e malattie infettive, Fondazione IRCCS Policlinico "San Matteo", Piazzale Golgi 19, 27100, Pavia (PV), Italy. Electronic address: rmaserati@smatteo.pv.it.
Mirella GherardiS.C. Medicina Legale, Azienda USL Valle d'Aosta, Località Amerique 7/L, 11020, Quart (AO), Italy. Electronic address: mgherardi@ausl.vda.it.
Maurizio CastelliS.C. Medicina Legale, Azienda USL Valle d'Aosta, Località Amerique 7/L, 11020, Quart (AO), Italy. Electronic address: mcastelli@ausl.vda.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-mortem swabs for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA detection have been recommended by several Scientific Committees and Institutions as a standard procedure for post-mortem assessment of potential Coronavirus Disease-19 (COVID-19) related deaths. To date there is no data about the SARS-CoV-2 RNA detectability period in human bodies after death. The present case documents the persistence of SARS-CoV-2 RNA in the upper respiratory tract 35-days after death. Post-mortem swabs could be used as a valuable tool in preventive evaluation of the risks-benefits ratio associated with autopsy execution. SARS-CoV-2 RNA post-mortem detection could have a key diagnostic role in deaths lacking medical assistance, unattended deaths, and patients with multiple comorbidities. Based on the present report, staged post-mortem swabs should be performed even after a long post-mortem interval.

Indexed as

CadaverHumansMaleMiddle AgedNasal CavityOropharynxReal-Time Polymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionRNA, ViralSARS-CoV-2Specimen HandlingTime FactorsRNA, ViralAutopsyBiosafetyCOVID-19Post-mortem diagnosisPost-mortem swabSARS-CoV-2

Identifiers

PMID33360242
PMCPMC7725267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.