ReviewJournal of sport and health science2021
Effects of interrupting prolonged sitting on postprandial glycemia and insulin responses: A network meta-analysis.
Review in Journal of sport and health science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Optimal exercise intensity for improving executive function in patients with attention deficit hyperactivity disorder: systematic review and network meta-analysis.European child & adolescent psychiatry · 2025Pooled it
- Short-term effects of brief stair climbing interruptions on postprandial hyperglycemia during prolonged sitting: a randomized cross-over trial.Scientific reports · 2025Trial
- Leg Fidgeting During Prolonged Sitting Improves Postprandial Glycemic Control in People with Obesity.Obesity (Silver Spring, Md.) · 2021Trial
- Management of type 2 diabetes, 2026. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).Diabetologia · 2026Article
- Exercise Snacks and Acute Postprandial Glucose and Insulin Metabolism: An Umbrella Review and De Novo Meta-Analysis.Metabolites · 2026Review
- Acute Effects of Interrupting Prolonged Sitting on Glucose, Insulin and Lipid Metabolism in Healthy Populations: A Three-Level Meta-Analysis.Metabolites · 2026Review
- Comparison of hourly walking and alternating walking-resistance breaks versus prolonged sitting on 26-h glucose responses in sedentary adults: a randomized crossover trial.Journal of exercise science and fitness · 2026Article
- Optimal exercise dose for glycemic control in prediabetes across different exercise types.iScience · 2025Article
- Short bouts of accumulated exercise: Review and consensus statement on definition, efficacy, feasibility, practical applications, and future directions.Journal of sport and health science · 2025Article
- Exercise snacks and physical fitness in sedentary populations.Sports medicine and health science · 2025Review
- Comparison of body mass index and physical activity levels of e-sportsmen.Frontiers in public health · 2025Article
- Research progress on zero-time exercise interventions in patients with chronic diseases: a narrative review.Frontiers in public health · 2025Review
- Effects of using wearable devices on reducing sedentary time and prolonged sitting in healthy adults: a network meta-analysis.BMJ open · 2024Article
- A Scoping Review of Acute Sedentary Behaviour Studies of People with Spinal Cord Injury.International journal of environmental research and public health · 2024Article
- Comment on "Exercise Snacks and Other Forms of Intermittent Physical Activity for Improving Health in Adults and Older Adults: A Scoping Review of Epidemiological, Experimental and Qualitative Studies".Sports medicine (Auckland, N.Z.) · 2024Article
- Effects of Physical Activity, VODiabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Association between physical activity and sedentary behavior and gestational diabetes mellitus: a Mendelian randomization analysis.Frontiers in endocrinology · 2024Article
- Physiology of sedentary behavior.Physiological reviews · 2023Review
- Free fatty acids and peripheral blood mononuclear cells (PBMC) are correlated with chronic inflammation in obesity.Lipids in health and disease · 2023Article
- Twenty-four-hour movement guidelines during adolescence and its association with obesity at adulthood: results from a nationally representative study.European journal of pediatrics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to evaluate the effectiveness of physical activity (PA) interrupting prolonged sitting (PS) on postprandial glycemia and insulin responses among adults.
methodsPubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, PsycINFO, and the China National Knowledge Infrastructure databases were searched through September 30, 2020. Randomized controlled trials (RCTs) that examined the effect of all forms of PA interrupting PS on postprandial glycemia and/or insulin responses among adults without chronic diseases were included in this study. The risk of bias of included studies was evaluated based on the Cochrane tool. A network meta-analysis was performed to estimate the summary standardized mean differences (SMDs) with 95% confidence intervals (95%CIs) with random effects.
resultsThirty crossover RCTs were included in our review. These RCTs included 9 types of interventions that interrupted PS. When compared to PS by itself, light-intensity PA intermittent interrupting (LPA-INT) PS and moderate-intensity PA intermittent interrupting (MPA-INT) PS significantly lowered postprandial glycemia (SMD = -0.46, 95%CI: -0.70 to -0.21; SMD = -0.69, 95%CI: -1.00 to -0.37, respectively) and significantly reduced postprandial insulin response (SMD = -0.46, 95%CI: -0.66 to -0.26; SMD = -0.47, 95%CI: -0.77 to -0.17, respectively). Results of the clustered ranking plot indicated that MPA-INT was the most effective intervention in lowering postprandial glycemia and insulin responses.
conclusionReplacing PS with MPA-INT or LPA-INT has a positive effect in reducing postprandial glycemia and insulin responses, with MPA-INT being the optimal intervention strategy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.