Evidence map›Paper›PMID 33359325›Full record

ArticleThe Journal of investigative dermatology2021

ALK3 Is Not Required for the Embryonic Development, Homeostasis, and Repopulation of Epidermal Langerhans Cells in Steady and Inflammatory States.

Qian Yu, Nirmal Parajuli, Qijun Yi, Yuji Mishina, James T Elder, Li Zhou, Qing-Sheng Mi

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207The Journal of investigative dermatology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qian YuCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, Michigan, USA; Immunology Research Program, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, Michigan, USA; Shanghai tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Nirmal ParajuliCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, Michigan, USA; Immunology Research Program, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, Michigan, USA.
Qijun YiCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, Michigan, USA; Immunology Research Program, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, Michigan, USA.
Yuji MishinaDepartment of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
James T ElderDepartment of Dermatology, University of Michigan School Medicine, Ann Arbor, Michigan, USA.
Li ZhouCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, Michigan, USA; Immunology Research Program, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, Michigan, USA; Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan, USA.
Qing-Sheng MiCenter for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health System, Detroit, Michigan, USA; Immunology Research Program, Henry Ford Cancer Institute, Henry Ford Health System, Detroit, Michigan, USA; Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan, USA. Electronic address: QMI1@hfhs.org.

Funding

Genetic and Genomic Dissection of Psoriatic ArthritisR01AR063611 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELDER, JAMES TILFORD, GLADMAN, DAFNA D · 2012 to 2023
$6.2M
microRNAs and NKT cell development and functionR01AI119041 · NIAID · HENRY FORD HEALTH SYSTEM · PI MI, QING-SHENG · 2016 to 2020
$1.8M
Roles of HDAC3 in Epidermal Langerhans Cell Ontogeny and FunctionR01AR069681 · NIAMS · HENRY FORD HEALTH SYSTEM · PI MI, QING-SHENG · 2016 to 2020
$1.7M
MicroRNAs regulate skin Langerhans cellsR01AR072046 · NIAMS · HENRY FORD HEALTH SYSTEM · PI ZHOU, LI · 2018 to 2022
$1.6M
Uncover the new subsets of epidermal Langerhans cellsR61AR076803 · NIAMS · HENRY FORD HEALTH SYSTEM · PI ADRIANTO, INDRA, MI, QING-SHENG · 2019 to 2020
$746k
Uncover the new subsets of epidermal Langerhans cellsR33AR076803 · NIAMS · HENRY FORD HEALTH SYSTEM · PI ADRIANTO, INDRA, MI, QING-SHENG · 2021 to 2021
$380k
NIAID NIH HHS R01 AI119041NIAMS NIH HHS R01 AR063611NIAMS NIH HHS R01 AR069681NIAMS NIH HHS R01 AR072046NIAMS NIH HHS R33 AR076803NIAMS NIH HHS R61 AR076803
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Embryonic DevelopmentAnimalsBone Morphogenetic Protein 7Bone Morphogenetic Protein Receptors, Type IDisease Models, AnimalEmbryo, MammalianHomeostasisHumansImiquimodLangerhans CellsMiceMice, KnockoutPsoriasisSeverity of Illness IndexSignal Transductionbmp7 protein, mouseBmpr1a protein, mouseBone Morphogenetic Protein 7Bone Morphogenetic Protein Receptors, Type IImiquimod

Identifiers

PMID33359325
PMCPMC8219812

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.