Evidence map›Paper›PMID 33359061›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Molecular epidemiology of COVID-19 in Oman: A molecular and surveillance study for the early transmission of COVID-19 in the country.

Samira Al-Mahruqi, Adil Al-Wahaibi, Abdul Latif Khan, Amina Al-Jardani, Sajjad Asaf, Hanan Alkindi, Samiha Al-Kharusi, Ahmed N Al-Rawahi, Ahmed Al-Rawahi, Majid Al-Salmani and 4 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  9. Review
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  13. Seroprevalence of SARS-CoV-2 antibodies in the general population of Oman: results from four successive nationwide sero-epidemiological surveys.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Samira Al-MahruqiDirectorate General for Disease Surveillance and Control, Ministry of Health, Sultanate of Oman, P.O. Box 393, PC 100 Muscat, Oman. Electronic address: samira.almahruqi@gmail.com.
Adil Al-WahaibiDirectorate General for Disease Surveillance and Control, Ministry of Health, Sultanate of Oman, P.O. Box 393, PC 100 Muscat, Oman. Electronic address: adilwahaibi@gmail.com.
Abdul Latif KhanNatural and Medical Sciences Research Center, University of Nizwa, P.O. Box 33, PC 616 Nizwa, Oman. Electronic address: abdullatif@unizwa.edu.om.
Amina Al-JardaniDirectorate General for Disease Surveillance and Control, Ministry of Health, Sultanate of Oman, P.O. Box 393, PC 100 Muscat, Oman. Electronic address: aksaljardani@gmail.com.
Sajjad AsafNatural and Medical Sciences Research Center, University of Nizwa, P.O. Box 33, PC 616 Nizwa, Oman. Electronic address: sajjadasaf@unizwa.edu.om.
Hanan AlkindiDirectorate General for Disease Surveillance and Control, Ministry of Health, Sultanate of Oman, P.O. Box 393, PC 100 Muscat, Oman. Electronic address: drhananalkindi@gmail.com.
Samiha Al-KharusiDirectorate General for Disease Surveillance and Control, Ministry of Health, Sultanate of Oman, P.O. Box 393, PC 100 Muscat, Oman. Electronic address: s_kharusi@hotmail.com.
Ahmed N Al-RawahiNatural and Medical Sciences Research Center, University of Nizwa, P.O. Box 33, PC 616 Nizwa, Oman. Electronic address: ahmed.alrawahi@unizwa.edu.om.
Ahmed Al-RawahiNatural and Medical Sciences Research Center, University of Nizwa, P.O. Box 33, PC 616 Nizwa, Oman. Electronic address: ahmed@unizwa.edu.om.
Majid Al-SalmaniNatural and Medical Sciences Research Center, University of Nizwa, P.O. Box 33, PC 616 Nizwa, Oman. Electronic address: majid.al.salmani@unizwa.edu.om.
Intisar Al-ShukriDirectorate General for Disease Surveillance and Control, Ministry of Health, Sultanate of Oman, P.O. Box 393, PC 100 Muscat, Oman. Electronic address: drintisar77@gmail.com.
Aisha Al-BusaidiDirectorate General for Disease Surveillance and Control, Ministry of Health, Sultanate of Oman, P.O. Box 393, PC 100 Muscat, Oman. Electronic address: a_al_busaidy@hotmail.com.
Seif Salem Al-AbriDirectorate General for Disease Surveillance and Control, Ministry of Health, Sultanate of Oman, P.O. Box 393, PC 100 Muscat, Oman. Electronic address: salabri@gmail.com.
Ahmed Al-HarrasiNatural and Medical Sciences Research Center, University of Nizwa, P.O. Box 33, PC 616 Nizwa, Oman. Electronic address: aharrasi@unizwa.edu.om.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been proven to be lethal to human health, which affects almost every corner of the world. The objectives of this study were to add context to the global data and international genomic consortiums, and to give insight into the efficiency of the contact tracing system in Oman.

methodsWe combined epidemiological data and whole-genome sequence data from 94 samples of SARS-CoV-2 in Oman to understand the origins, genetic variation, and transmissibility. The whole-genome size of sequence data was obtained through a customized SARS-COV-2 research panel. Amplifier methods ranged from 26 Kbp to 30 Kbp and were submitted to GISAID.

findingsThe study found that P323L (94.7%) is the most common mutation, followed by D614G (92.6%) Spike protein mutation. A unique mutation, I280V, was first reported in Oman and was associated with a rare lineage, B.1.113 (10.6%). In addition, the study revealed a good agreement between genetic and epidemiological data.

interpretationOman's robust surveillance system was very efficient in guiding the outbreak investigation processes in the country, the study illustrates the future importance of molecular epidemiology in leading the national response to outbreaks and pandemics.

Indexed as

PandemicsAdolescentAdultChildChild, PreschoolCOVID-19Epidemiological MonitoringFemaleGenome, ViralHumansInfantMaleMiddle AgedMolecular EpidemiologyMutationOmanCladeCOVID-19 epidemiologyMutationOmanPhylogenomic analysisSARS-CoV-2

Identifiers

PMID33359061
PMCPMC7834852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.