Evidence map›Paper›PMID 33358996›Full record

ArticleMolecular and cellular neurosciences2021

Inhibitory signaling in mammalian olfactory transduction potentially mediated by Gα

Elizabeth A Corey, Kirill Ukhanov, Yuriy V Bobkov, Jeremy C McIntyre, Jeffrey R Martens, Barry W Ache

Open access · hybridAbstract read
In one paragraph

Article in Molecular and cellular neurosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Reduced CaFrontiers in neuroscience · 2022
    Article
  9. A physicochemical model of odor sampling.PLoS computational biology · 2021
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elizabeth A CoreyWhitney Laboratory, Center for Smell and Taste, University of Florida, Gainesville, FL 32610, United States of America.
Kirill UkhanovDept. of Pharmacology and Therapeutics, Center for Smell and Taste, University of Florida, Gainesville, FL 32610, United States of America.
Yuriy V BobkovWhitney Laboratory, Center for Smell and Taste, University of Florida, Gainesville, FL 32610, United States of America.
Jeremy C McIntyreDept. of Neuroscience, Center for Smell and Taste, University of Florida, Gainesville, FL 32610, United States of America.
Jeffrey R MartensDept. of Pharmacology and Therapeutics, Center for Smell and Taste, University of Florida, Gainesville, FL 32610, United States of America.
Barry W AcheWhitney Laboratory, Dept. of Biology, Center for Smell and Taste, University of Florida, Gainesville, FL 32610, United States of America; Whitney Laboratory, Dept. of Neuroscience, Center for Smell and Taste, University of Florida, Gainesville, FL 32610, United States of America. Electronic address: bwa@whitney.ufl.edu.
University of Florida · USTaste and Smell Clinic · US

Funding

Olfactory Singaling, Cilia, and Sensory DisordersR01DC009606 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARTENS, JEFFREY · 2008 to 2018
$4.1M
MULTIPLE PATHWAYS IN OLFACTORY TRANSDUCTIONR01DC001655 · NIDCD · UNIVERSITY OF FLORIDA · PI ACHE, BARRY W. · 1992 to 2010
$3.0M
Phosphoinositide Signaling in Mammalian OlfactionR01DC005995 · NIDCD · UNIVERSITY OF FLORIDA · PI ACHE, BARRY W. · 2003 to 2015
$3.0M
Rescue of channelopathy induced anosmiasR00DC013555 · NIDCD · UNIVERSITY OF FLORIDA · PI MCINTYRE, JEREMY · 2016 to 2018
$747k
Rescue of channelopathy induced anosmiasK99DC013555 · NIDCD · UNIVERSITY OF FLORIDA · PI MCINTYRE, JEREMY · 2014 to 2015
$202k
NIDCD NIH HHS K99 DC013555NIDCD NIH HHS R00 DC013555NIDCD NIH HHS R01 DC001655NIDCD NIH HHS R01 DC005995NIDCD NIH HHS R01 DC009606
6 · The paper itself

Abstract

Olfactory GPCRs (ORs) in mammalian olfactory receptor neurons (ORNs) mediate excitation through the Gα

Indexed as

AnimalsCells, CulturedFemaleGTP-Binding Protein alpha Subunits, Gi-GoHEK293 CellsHumansMiceMice, Inbred C57BLOlfactory Receptor NeuronsPhosphatidylinositol 3-KinasesRatsRats, Sprague-DawleySignal TransductionGNAO1 protein, mouseGTP-Binding Protein alpha Subunits, Gi-GoPhosphatidylinositol 3-KinasesCombinatorial codingInhibitionModulationOlfactionOlfactory receptor neurons

Identifiers

PMID33358996
PMCPMC9060814
OpenAlexW3118077010

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.