ArticleThe Journal of pediatrics2021
Electrocardiographic Changes in Children with Multisystem Inflammation Associated with COVID-19: Associated with Coronavirus Disease 2019.
Article in The Journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Longitudinal Cardiac Outcomes of Multisystem Inflammatory Syndrome in Children: A Systematic Review and Meta-Analysis.Pediatric cardiology · 2023Pooled it
- Management of long COVID-19 in children and adolescents: from diagnosis to therapeutically approaches.Annals of medicine · 2026Review
- Community-acquired pneumonia alters circadian regulation of cardiac electrophysiology in children.European journal of pediatrics · 2026Article
- Article
- An Update on Multi-System Inflammatory Syndrome in Children.Current rheumatology reports · 2025Review
- Comparison of Cardiac Findings in Pediatric Patients with Multisystem Inflammatory Syndrome in Children Associated with COVID-19.Sisli Etfal Hastanesi tip bulteni · 2025Article
- Postacute Sequelae of SARS-CoV-2 in Children.Pediatrics · 2024Review
- Pathophysiological correlations between SARS-CoV-2 and arrhythmogenesis: a literature review.Germs · 2024Review
- Cardiovascular Manifestations of Multisystem Inflammatory Syndrome in Children: A Single-Center Bulgarian Study.Medicina (Kaunas, Lithuania) · 2023Observational
- Year 2022: exploring COVID-19 pandemic in children.Italian journal of pediatrics · 2023Review
- Article
- Atrial Fibrillation as a Rare Complication of Multisystem Inflammatory Syndrome in Children (MIS-C): A Case Report.Cureus · 2023Article
- Arrhythmias in pediatric patients with COVID-19.Clinical and experimental pediatrics · 2023Article
- COVID-19 and Cardiac Implications-Still a Mystery in Clinical Practice.Reviews in cardiovascular medicine · 2023Review
- Arrhythmia and COVID-19 in children.Clinical and experimental pediatrics · 2023Article
- Article
- Analysis of cardiac manifestation and treatment of multisystem inflammatory syndrome in children related to SARS-CoV-2.Biomolecules & biomedicine · 2023Article
- Echocardiographic Findings and Conduction Abnormalities in Children with Multisystem Inflammatory Syndrome.Indian journal of pediatrics · 2023Article
- Evaluation of late cardiac effects after multisystem inflammatory syndrome in children.Frontiers in pediatrics · 2023Article
- Long-Term Cardiovascular Outcome in Children with MIS-C Linked to SARS-CoV-2 Infection-An Italian Multicenter Experience.Biology · 2022Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze findings and trends on serial electrocardiograms (ECGs) in multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease taken during the course of illness and at follow-up. STUDY
designWe included all children presenting with MIS-C at a single center with 3 or more ECGs taken during the course of their illness. We measured ECG intervals (PR, QRSd, and QTc) and amplitudes (R-, S-, and T-waves) on each ECG and documented any arrhythmias and ST-segment changes.
resultsA majority of children (n = 42, 67%) showed ECG changes. The most common findings were low QRS amplitudes and transient T-wave inversion. ST changes were uncommon and included ST-segment elevation consistent with pericarditis in 1 child and acute coronary ischemia in 1 child. Arrhythmias were seen in 13 children (21%) but were benign with the exception of 1 child who was compromised by an atrial tachycardia requiring support with extracorporeal membrane oxygenation. No children were found to have high-grade atrioventricular block.
conclusionsMIS-C is associated with electrocardiographic changes over the course of the illness, with low amplitude ECGs on presentation, followed by transient T-wave inversion, particularly in the precordial leads. There was a low prevalence of ST-segment changes and tachyarrhythmias.
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