Evidence map›Paper›PMID 33358740›Full record

ArticleJournal of cardiothoracic and vascular anesthesia2021

Primary Stroke and Failure-to-Rescue Following Thoracic Endovascular Aortic Aneurysm Repair.

Christian Mpody, Jerry Cui, Hamdy Awad, Sujatha Bhandary, Michael Essandoh, Ronald L Harter, Joseph D Tobias, Olubukola O Nafiu

Abstract read
In one paragraph

Article in Journal of cardiothoracic and vascular anesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christian MpodyDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH.
Jerry CuiDepartment of Anesthesiology and Pain Medicine, The Ohio State University, Columbus, OH.
Hamdy AwadDepartment of Anesthesiology and Pain Medicine, The Ohio State University, Columbus, OH.
Sujatha BhandaryDepartment of Anesthesiology and Pain Medicine, The Ohio State University, Columbus, OH.
Michael EssandohDepartment of Anesthesiology and Pain Medicine, The Ohio State University, Columbus, OH.
Ronald L HarterDepartment of Anesthesiology and Pain Medicine, The Ohio State University, Columbus, OH.
Joseph D TobiasDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH.
Olubukola O NafiuDepartment of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH. Electronic address: Olubukola.Nafiu@nationwidechildrens.org.

Funding

Identifying effective therapies to prevent paralysis after aortic aneurysm repair surgeryR21NS113097 · NINDS · OHIO STATE UNIVERSITY · PI ELSAYED-AWAD, HAMDY M., TILI, ESMERINA · 2019 to 2019
$429k
NINDS NIH HHS R21 NS113097
6 · The paper itself

Abstract

objectiveTo characterize the impact, on failure to rescue, of cerebrovascular accident as a first postoperative complication after thoracic endovascular aortic aneurysm repair (TEVAR).

designA retrospective cohort study using of National Surgical Quality Improvement Program Participants User File.

settingUnited States hospitals taking part in the National Surgical Quality Improvement Program.

participantsPatients >18 years, who underwent TEVAR for nonruptured thoracic aortic aneurysm between 2005 and 2018, and developed one or more major postoperative complications within 30 days after surgery.

interventionsNone. MEASUREMENTS AND MAIN

resultsOut of 3,937 patients who underwent TEVAR for nonruptured thoracic aneurysm, 1,256 (31.9%) developed major postoperative complications (stroke incidence: 11.4% [143/1256]). In adults <65 years old, the occurrence of stroke as the primary complication, relative to the occurrence of other complications, was associated with ten times greater risk of failure to rescue (29.4% v 4.6%; odds ratio [OR]: 10.10; 95% confidence interval [CI] 2.45-41.56; p < 0.001). The effect size was relatively lower when stroke occurred but was not the primary complication (20.0% v 4.6%; OR: 7.55; 95% CI 1.37-41.71; p = 0.020). In patients ≥65 years, the occurrence of stroke as the primary complication did not carry the similar prognostic value.

conclusionYounger patients who developed stroke were up to ten times more likely to die, relative to patients who developed other major complications. Survival was substantially reduced when stroke was the primary complication. The authors' findings imply that to maximize the survival of patients undergoing TEVAR, efforts may be needed to predict and prevent stroke occurrence as a primary postoperative morbidity event.

Indexed as

Aortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationEndovascular ProceduresStrokeAdultAgedHumansPostoperative ComplicationsRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited Statesfailure to rescueneurologic complicationsstrokeTEVAR

Identifiers

PMID33358740
PMCPMC8667044

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.