SynthesisBrazilian journal of physical therapy
Effectiveness of virtual reality in children and young adults with cerebral palsy: a systematic review of randomized controlled trial.
Synthesis in Brazilian journal of physical therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Home-based telerehabilitation on motor function in youth with cerebral palsy: systematic review and meta-analysis.Pediatric research · 2026Pooled it
- Effectiveness of interventions using activity trackers and smartphone applications for increasing physical activity in older adults with health conditions: a systematic review with meta-analysis.The Journal of frailty & aging · 2026Pooled it
- Effect of virtual reality technology on balance ability intervention in stroke patients: a systematic review and meta-analysis.Frontiers in physiology · 2026Pooled it
- Effectiveness of emerging technology-assisted rehabilitation in children with cerebral palsy: a systematic review and meta-analysis.Frontiers in neurology · 2026Pooled it
- Effectiveness of virtual reality for functional disorders in cerebral palsy: an overview of systematic reviews and meta-analyses.Frontiers in neurology · 2025Pooled it
- NintendoInternational journal of environmental research and public health · 2022Pooled it
- Trial
- Comparative effects of kinect-based versus therapist-based constraint-induced movement therapy on motor control and daily motor function in children with unilateral cerebral palsy: a randomized control trial.Journal of neuroengineering and rehabilitation · 2023Trial
- A methodologic survey on use of the GRADE approach in evidence syntheses published in high-impact factor neurology journals.Systematic reviews · 2026Article
- Effects of Telerehabilitation on Gross Motor Function in Children with Cerebral Palsy: A Systematic Review.Healthcare (Basel, Switzerland) · 2026Review
- Cerebral cortical activation and functional connectivity characteristics of children with unilateral cerebral palsy during a single-session virtual reality throwing motor task: a functional near-infrared spectroscopy study.Frontiers in rehabilitation sciences · 2026Article
- Effectiveness of Virtual Reality-Based Physiotherapy Interventions on Pain, Range of Motion, and Gait Function in a Juvenile Hip Arthritis Patient: A Case Report.Case reports in medicine · 2026Article
- Effects of Virtual Reality Use on Children with Cerebral Palsy and Its Applications in Health: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- The Impact of Virtual-Reality-Based Physiotherapy on Upper Limb Function in Children with Cerebral Palsy.Journal of clinical medicine · 2025Review
- Exploring cortical excitability in children with cerebral palsy through lower limb robot training based on MI-BCI.Scientific reports · 2025Article
- Augmented Reality Exergames for Upcoming Cognitive-Motor Rehabilitation: User-Centered Design Approach and User Experience of Healthy Children.JMIR rehabilitation and assistive technologies · 2025Article
- Virtual reality-based fine motor skills training in paediatric rehabilitation: a protocol for a scoping review.BMJ open · 2025Article
- The impact of asthma education grounded in virtual reality technology upon the quality of life of pediatric patients with bronchial asthma.Frontiers in pediatrics · 2025Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCerebral palsy (CP) is one of the main causes of disability in childhood. Virtual reality (VR) has been used as a treatment option in this population, however its effectiveness is unclear.
objectiveTo evaluate the effectiveness of VR in patients with CP.
methodsWe conducted electronic searches in EMBASE, MEDLINE, Cochrane library, PEDro, AMED, PsycoINFO, and LILACS databases and trial site registries such as ClinicalTrials.gov and ICTRP. We included randomized controlled trials that tested the use of VR alone or in combination with other interventions compared to more conventional rehabilitation or usual care in individuals with CP. The primary outcomes were upper and lower limb function, postural control, and balance. The secondary outcomes included global motor function, perception, cognition and spatial functions, motivation, motor learning, and adverse events. Two independent reviewers extracted and assessed included articles for risk of bias using the Cochrane risk of bias tool. We use a meta-analysis with random effect model whenever possible. We analyzed the quality of evidence using theGRADE approach.
resultsWe included 38 trials (pooled n = 1233 participants) in this review. There is very low quality of evidence that VR plus conventional rehabilitation is better than conventional rehabilitation for upper limb function. There is also very low quality evidence that VR alone is no better than conventional rehabilitation for upper and lower limb function. No adverse events were observed among the 10 trials that provided information on this outcome.
conclusionAt present we have very limited to limited confidence in effect estimation for utilization of VR in this population. Future studies may change our confidence in results and effect estimates. PROTOCOL REGISTRATION: PROSPERO CRD 42018102759.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.