Evidence map›Paper›PMID 33358656›Full record

ReviewJournal of science and medicine in sport2021

Temperature regulation during exercise in the heat: Insights for the aging athlete.

W Larry Kenney, S Tony Wolf, Gabrielle A Dillon, Craig W Berry, Lacy M Alexander

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Journal of science and medicine in sport, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07482046 (Effectiveness of Topical Menthol as A Cooling Method During Exercise in A Recreational Runner Population), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07482046 phase2 / phase3completednot on this mapstarted 2023, after this paper: background citation

Effectiveness of Topical Menthol as A Cooling Method During Exercise in A Recreational Runner Population

TypeinterventionalSponsorTaisho Pharmaceutical IndonesiaRan2023 to 2023Enrolled37ConditionsHeat Stress, Athletic PerformanceArmsLight blue gel with the trademark Counterpain COOL® (License Number: POM QD. 111 709 501) containing the active substance Menthol 4%., Placebo
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Sweat glands in action: the role of biological and environmental factors, exercise, and dermatologic conditions in sudomotor function.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Validation of livability environmental limits to heat and humidity.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Biomarkers of aging.Science China. Life sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

W Larry KenneyDepartment of Kinesiology, The Pennsylvania State University, United States; The Graduate Program in Physiology, The Pennsylvania State University, United States.
S Tony WolfDepartment of Kinesiology, The Pennsylvania State University, United States. Electronic address: saw85@psu.edu.
Gabrielle A DillonDepartment of Kinesiology, The Pennsylvania State University, United States.
Craig W BerryDepartment of Kinesiology, The Pennsylvania State University, United States.
Lacy M AlexanderDepartment of Kinesiology, The Pennsylvania State University, United States.
Pennsylvania State University · US

Funding

Identification of Critical Thermal Environments for Aged AdultsR01AG067471 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI KENNEY, W. LARRY · 2020 to 2024
$3.7M
NIA NIH HHS R01 AG067471
6 · The paper itself

Abstract

objectiveThe purpose of this review is to evaluate the currently-available literature regarding the impact of both primary aging and age-related fitness on thermoregulatory function during exercise in the heat. In so doing, we aim to (1) characterize the influence of fitness in mitigating age-related declines in thermoregulation, (2) address the limitations of prior experimental approaches for investigating age-related thermoregulatory impairments, (3) examine to what extent aerobic fitness can be maintained in the aging athlete, and (4) begin to address the specific environmental conditions in which age-related impairments in thermoregulatory function may place highly active older adults at increased risk for heat-related illness and injury and/or limited performance.

designMini-review.

methodsReview and synthesis of available information.

resultsThe earth's climate is warming, accompanied by a consequently greater frequency and severity of extreme heat events. At the same time, lifespan is increasing and people of all ages are staying increasingly active. Age-related impairments in thermoregulatory function are well-documented, leading to increased heat-related health risks and reduced exercise/athletic performance for older adults in hot environmental conditions. High aerobic fitness improves body temperature regulation during exercise via augmented sweating and improved cardiovascular function, including cardiac output and skin blood flow, in humans of all ages.

conclusionsThe masters athlete is better suited for exercise/heat-stress compared to his or her less fit peers. However, while age and thermoregulation in general has been studied extensively, research on the most fit older adults, including highly competitive athletes, is generally lacking.

Indexed as

Body Temperature RegulationHot TemperatureAdolescentAdultAgedAgingCardiac OutputExerciseHeat Stress DisordersHumansMiddle AgedPhysical Conditioning, HumanPhysical FitnessRegional Blood FlowRisk FactorsSkinBody temperatureExercise trainingHeat stressSkin blood flowSweating

Identifiers

PMID33358656
PMCPMC8222413
OpenAlexW3116187951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.