ReviewIndian heart journal
Opium and cardiovascular health: A devil or an angel?
Review in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Opium Use and Cancer Risk: A Comprehensive Systematic Review and Meta-Analysis of Observational Studies.International journal of clinical practice · 2022Pooled it
- Postoperative outcomes of combined interpectoral-pectoserratus versus combined deep-superficial serratus anterior plane blocks in minimally invasive coronary artery bypass surgery: A prospective randomized study.Scientific reports · 2026Trial
- Machine learning prediction of physician-assigned treatment categories from pre-procedural electronic medical record data in cardiac patients: A multiclass classification study.PLOS digital health · 2026Article
- Potential Effects of Opium on Pro-inflammatory Cytokines in Coronary Artery Disease by Interfering with Anti-inflammatory Drugs.Current molecular medicine · 2026Article
- The Association Between Opium Consumption, Diabetes, and Hypertension Among Male Participants in the Tabari Cohort Population: A Cross-sectional Study.Journal of research in health sciences · 2026Article
- Effects of opium on hippocampal-dependent memory, antioxidant enzyme levels, oxidative stress markers, and histopathological changes of rat hippocampus.Biochemistry and biophysics reports · 2025Article
- Effects of opium on cholesterol metabolism in rats fed normal and high-fat/high-cholesterol diet.Toxicology reports · 2025Article
- Sonographic features of internal carotid artery in patients with opioid use disorder: Is opium a new risk factor for atherosclerosis of internal carotid artery?Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025Article
- Investigating the relationship between opium use and coronary slow flow: a propensity score matched case-control study.BMJ open · 2024Article
- Potential impact of controlling opium use prevalence on future cancer incidence in Iran.EClinicalMedicine · 2024Article
- Prevalence of major non-communicable diseases and their associated risk factors in Afghanistan: a systematic review and meta-analysis.Therapeutic advances in chronic disease · 2024Review
- Long-Term Effects of Opium Consumption Following Percutaneous Coronary Intervention: A 10-year Follow-Up Study.Global heart · 2024Article
- Investigating the Relationship between Carotid Intima-Media Thickness (CIMT), Opium Addiction, and Components of the Metabolic Syndrome.Addiction & health · 2023Article
- Effects of opium use on one-year major adverse cardiovascular events (MACE) in the patients with ST-segment elevation MI undergoing primary PCI: a propensity score matched - machine learning based study.BMC complementary medicine and therapies · 2023Article
- Association between Nontraditional Risk Factors and Calculated 10-Year Risk of Atherosclerotic Cardiovascular Disease in a Large General Population: Based on the Pars Cohort Study.The journal of Tehran Heart Center · 2023Article
- Does Opioid Addiction Influence Clinical and Angiographic Outcomes in STEMI Patients Undergoing Emergency PCI?Advanced biomedical research · 2023Article
- Prevalence and trends of coronary artery disease risk factors and their effect on age of diagnosis in patients with established coronary artery disease: Tehran Heart Center (2005-2015).BMC cardiovascular disorders · 2021Article
- Clusters of the Risk Markers and the Pattern of Premature Coronary Heart Disease: An Application of the Latent Class Analysis.Frontiers in cardiovascular medicine · 2021Article
- How is Nursing Care Provided for Cardiovascular Patients with Substance Use Disorders?Iranian journal of nursing and midwifery researchArticle
- Challenges to Lifestyle Medicine for Type 2 Diabetes in Iran: A Synoptic Review.American journal of lifestyle medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Opioids have the highest rate of illicit drug consumption after cannabis worldwide. Opium, after tobacco, is still the most commonly abused substance in the Middle East. In addition to the ease of availability, one reason for the high consumption of opium in Asian countries might be a traditional belief among Eastern people and even medical staff that opium may have ameliorating effects on cardiovascular diseases (CVDs) as well as diabetes mellitus, hypertension, and dyslipidemia. Over the last decade, many studies have been performed on humans and animals to evaluate the interplay between opium consumption and stable coronary artery disease, acute coronary syndromes, and atherosclerosis. In this review, we conclude that opium consumption should be considered a risk factor for CVDs. Healthy individuals, as well as cardiac and diabetic patients, should be informed and educated about the hazardous effects of opium consumption on cardiovascular and other chronic diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.