ArticleJACC. Clinical electrophysiology2020
Multicenter Study of Dynamic High-Density Functional Substrate Mapping Improves Identification of Substrate Targets for Ischemic Ventricular Tachycardia Ablation.
Article in JACC. Clinical electrophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Heterogeneity of outcomes reporting in catheter ablation trials for ventricular tachycardia: a systematic review.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Pooled it
- Three-Dimensional Perspective on Scar-Related Ventricular Tachycardia Substrate: Critical Conduction Abnormalities as Ablation Targets and Implications for Procedural Endpoints.Reviews in cardiovascular medicine · 2026Review
- Functional Substrate Mapping in Ablation for Scar-Related Ventricular Tachycardia.Reviews in cardiovascular medicine · 2026Review
- Outcomes of Focused Double Extrastimuli Mapping and Ablation in Ventricular Tachycardia.Journal of cardiovascular electrophysiology · 2026Article
- Utility of omnipolar mapping-guided cavotricuspid isthmus block.Heart rhythm O2 · 2025Article
- Outcomes of functional ventricular tachycardia ablation vs. medical therapy in Chagas cardiomyopathy patients with implantable cardioverter-defibrillators: a competing risks analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- JCS/JHRS 2024 Guideline Focused Update on Management of Cardiac Arrhythmias.Journal of arrhythmia · 2025Article
- Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- To the Editor- Functional substrate mapping of ventricular arrhythmia.Heart rhythm O2 · 2025Article
- Effect of Spatial Resolution on Accurate Detection and Localization of Arrhythmia Rotors in Human Right Ventricular Tachycardia.Journal of cardiovascular development and disease · 2024Article
- Detailed analysis of electrogram peak frequency to guide ventricular tachycardia substrate mapping.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- Catheter Ablation of Ventricular Tachycardia in Ischemic Heart Disease: What Is Known and New Perspectives.Current heart failure reports · 2024Review
- Optimal catheter ablation procedure for premature ventricular contraction originating from the free wall of tricuspid annulus.Clinical cardiology · 2024Article
- Functional Substrate Mapping: A New Frontier in the Treatment of Ventricular Tachycardia in Structural Heart Disease.Arrhythmia & electrophysiology review · 2024Review
- Ablation targets of scar-related ventricular tachycardia identified by dynamic functional substrate mapping.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023Article
- Optimization of decrementing evoked potential mapping for functional substrate identification in ischaemic ventricular tachycardia ablation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Wavefront directionality and decremental stimuli synergistically improve identification of ventricular tachycardia substrate: insights from personalized computational heart models.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- The value of functional substrate mapping in ventricular tachycardia ablation.Heart rhythm O2 · 2023Review
- Ventricular Tachycardia Ablation Guided by Functional Substrate Mapping: Practices and Outcomes.Journal of cardiovascular development and disease · 2022Review
- Contemporary Management of Complex Ventricular Arrhythmias.Arrhythmia & electrophysiology review · 2022Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesThe goal of this study was to evaluate the role of dynamic substrate changes in facilitating conduction delay and re-entry in ventricular tachycardia (VT) circuits.
backgroundThe presence of dynamic substrate changes facilitate functional block and re-entry in VT but are rarely studied as part of clinical VT mapping.
methodsThirty patients (age 67 ± 9 years; 27 male subjects) underwent ablation. Mapping was performed with the Advisor HD Grid multipolar catheter. A bipolar voltage map was obtained during sinus rhythm (SR) and right ventricular sense protocol (SP) single extra pacing. SR and SP maps of late potentials (LP) and local abnormal ventricular activity (LAVA) were made and compared with critical sites for ablation, defined as sites of best entrainment or pace mapping. Ablation was then performed to critical sites, and LP/LAVA identified by the SP.
resultsAt a median follow-up of 12 months, 90% of patients were free from antitachycardia pacing (ATP) or implantable cardioverter-defibrillator shocks. SP pacing resulted in a larger area of LP identified for ablation (19.3 mm
conclusionsLP and LAVA observed during the SP were able to identify regions critical for ablation in VT with a greater accuracy than SR mapping. This may improve substrate characterization in VT ablation. The combination of ablation to critical sites and SP-derived LP/LAVA requires further assessment in a randomized comparator study.
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