Evidence map›Paper›PMID 33357444›Full record

ArticleCell reports2020

Rapid Precision Functional Mapping of Individuals Using Multi-Echo fMRI.

Charles J Lynch, Jonathan D Power, Matthew A Scult, Marc Dubin, Faith M Gunning, Conor Liston

3 registry-linked trialsAbstract read
In one paragraph

Article in Cell reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 132 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06144294 nanot yet recruitingnot on this mapstarted 2028, after this paper: background citation

Whole-Body Hyperthermia for Mood and Anxiety Disorders

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2028 to 2032Enrolled240ConditionsPostpartum Depression, Mood Disorders, Anxiety Disorders, Postpartum AnxietyArmsWhole-Body Hyperthermia, fMRI
NCT06606925 nacompletednot on this mapstarted 2023, after this paper: background citation

Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training

TypeinterventionalSponsorThe Geneva FoundationRan2023 to 2026Enrolled35ConditionsCognitive PerformanceArmsfMRI with virtual reality flight simulator
NCT07024875 recruitingnot on this mapstarted 2025, after this paper: background citation

Precision Neuroimaging of Parkinson's Disease

Typeobservational_patient_registrySponsorWashington University School of MedicineRan2025 to 2031Enrolled120ConditionsParkinsons Disease (PD)
3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Trial
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  6. Individualized Network Topography in Pre-adolescent Children and Adults Using Naturalistic Precision fMRI.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
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  9. Targeting mechanisms of change as a path to precision psychotherapy for community settings.Psychotherapy research : journal of the Society for Psychotherapy Research · 2026
    Article
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  16. Review
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72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charles J LynchDepartment of Psychiatry, Weill Cornell Medicine, New York, NY 10021, USA. Electronic address: cjl2007@med.cornell.edu.
Jonathan D PowerDepartment of Psychiatry, Weill Cornell Medicine, New York, NY 10021, USA.
Matthew A ScultDepartment of Psychiatry, Weill Cornell Medicine, New York, NY 10021, USA.
Marc DubinDepartment of Psychiatry, Weill Cornell Medicine, New York, NY 10021, USA.
Faith M GunningDepartment of Psychiatry, Weill Cornell Medicine, New York, NY 10021, USA.
Conor ListonDepartment of Psychiatry, Weill Cornell Medicine, New York, NY 10021, USA. Electronic address: col2004@med.cornell.edu.

Funding

Efficacy of biomarker-guided rTMS for treatment resistant depressionR01MH118388 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI BHATI, MAHENDRA T, GUNNING, FAITH M · 2019 to 2025
$6.2M
Atherosclerosis in cocaine addiction: imaging risk with PET/MRR01DA049547 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Nelly Alia-Klein, Zahi A. Fayad · 2022 to 2026
$3.9M
Diagnostic and prognostic biomarkers for subtypes of addiction-related circuit dysfunctionR01DA047851 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI GOLDSTEIN, RITA Z, LISTON, CONOR M · 2019 to 2022
$2.4M
Diagnostic Neuroimaging Biomarkers of Dysfunctional Valence Systems in Depression and AnxietyR56MH114976 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUNNING, FAITH M, LISTON, CONOR M · 2018 to 2018
$724k
Targeting salience network dysfunction in depression with individualized brain network mapping and TMSF32MH120989 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI LYNCH, CHARLES JOSEPH · 2019 to 2021
$194k
NIDA NIH HHS R01 DA047851NIDA NIH HHS R01 DA049547NIMH NIH HHS F32 MH120989NIMH NIH HHS R01 MH118388NIMH NIH HHS R56 MH114976
6 · The paper itself

Abstract

Resting-state functional magnetic resonance imaging (fMRI) is widely used in cognitive and clinical neuroscience, but long-duration scans are currently needed to reliably characterize individual differences in functional connectivity (FC) and brain network topology. In this report, we demonstrate that multi-echo fMRI can improve the reliability of FC-based measurements. In four densely sampled individual humans, just 10 min of multi-echo data yielded better test-retest reliability than 30 min of single-echo data in independent datasets. This effect is pronounced in clinically important brain regions, including the subgenual cingulate, basal ganglia, and cerebellum, and is linked to three biophysical signal mechanisms (thermal noise, regional variability in the rate of T

Indexed as

Brain MappingEcho-Planar ImagingHumansMagnetic Resonance ImagingPrecision Medicinefunctional brain networksmulti-echo fMRIprecision functional mappingtest-retest reliability

Identifiers

PMID33357444
PMCPMC7792478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.