Evidence map›Paper›PMID 33357443›Full record

ArticleCell reports2020

Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.

Anthony Bochler, Jailson Brito Querido, Terezie Prilepskaja, Heddy Soufari, Angelita Simonetti, Mayara Lucia Del Cistia, Lauriane Kuhn, Aline Rimoldi Ribeiro, Leoš Shivaya Valášek, Yaser Hashem

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  9. Ribosome Structural Changes Dynamically Affect Ribosome Function.International journal of molecular sciences · 2024
    Review
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  14. Review
  15. Article
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  18. Virulence · 2022
    Article
  19. Article
  20. Interactions of theParasitology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Anthony BochlerINSERM U1212 (ARNA), Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac 33607, France.
Jailson Brito QueridoINSERM U1212 (ARNA), Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac 33607, France; CNRS UPR9002 (ARN), Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, Strasbourg 67000, France.
Terezie PrilepskajaLaboratory of Regulation of Gene Expression, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic; Charles University, Faculty of Science, Albertov 6, 128 00 Prague 2, Czech Republic.
Heddy SoufariINSERM U1212 (ARNA), Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac 33607, France.
Angelita SimonettiCNRS UPR9002 (ARN), Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, Strasbourg 67000, France.
Mayara Lucia Del CistiaINSERM U1212 (ARNA), Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac 33607, France.
Lauriane KuhnUniversité de Strasbourg, CNRS, Plateforme Protéomique Strasbourg-Esplanade FRC 1589, Strasbourg 67000, France.
Aline Rimoldi RibeiroINSERM U1212 (ARNA), Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac 33607, France.
Leoš Shivaya ValášekLaboratory of Regulation of Gene Expression, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic.
Yaser HashemINSERM U1212 (ARNA), Institut Européen de Chimie et Biologie, Université de Bordeaux, Pessac 33607, France. Electronic address: yaser.hashem@inserm.fr.
Université de Bordeaux · FRCentre National de la Recherche Scientifique · FRCzech Academy of Sciences · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canonical mRNA translation in eukaryotes begins with the formation of the 43S pre-initiation complex (PIC). Its assembly requires binding of initiator Met-tRNA

Indexed as

AnimalsMammalsModels, MolecularProtein BiosynthesisTrypanosomatinacryo-EMeIF1eIF2eIF3eIF5-CTDES6(S)ES7(S)ES9(S)k-DDX60the 43S pre-initiation complextranslation initiationTrypanosoma cruzi

Identifiers

PMID33357443
PMCPMC7773551
OpenAlexW3115922066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.