ArticleNeuron2020
The Ups and Downs of the Striatum: Dopamine Biases Upstate Balance of Striosomes and Matrix.
Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Noninvasive Mapping of Striosome-Matrix Imbalance in Early Psychosis.Biological psychiatry global open science · 2026Article
- Whole-brain input organization ofFrontiers in neural circuits · 2026Article
- Patchy striatonigral neurons modulate locomotor vigor in response to environmental valence.eLife · 2025Article
- Patchy Striatonigral Neurons Modulate Locomotor Vigor in Response to Environmental Valence.bioRxiv : the preprint server for biology · 2025Article
- Dopamine release plateau and outcome signals in dorsal striatum contrast with classic reinforcement learning formulations.Nature communications · 2024Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prager et al. demonstrate an opposite regulation of activity in striosomes and matrix of the striatum. By a D1-receptor-linked L-VGCC-dependent mechanism, dopamine release can extend upstates in matrix D1-expressing direct pathway projection neurons (dSPNs) but shorten them in striosomal dSPNs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.