ArticleNeuron2021
The sensory representation of causally controlled objects.
Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Real-time closed-loop feedback system for mouse mesoscale cortical signal and movement control.eLife · 2026Article
- The Secondary Motor Cortex-External Globus Pallidus Pathway Regulates Auditory Feedback of Volitional Control.Neuroscience bulletin · 2026Article
- Article
- Why is everyone talking about brain state?Trends in neurosciences · 2023Review
- Neural Plasticity in Sensorimotor Brain-Machine Interfaces.Annual review of biomedical engineering · 2023Review
- How far neuroscience is from understanding brains.Frontiers in systems neuroscience · 2023Article
- Review
- Multiregion neuronal activity: the forest and the trees.Nature reviews. Neuroscience · 2022Review
- Volitional Generation of Reproducible, Efficient Temporal Patterns.Brain sciences · 2022Article
- Dynamic reorganization of the cortico-basal ganglia-thalamo-cortical network during task learning.Cell reports · 2022Article
- Building bridges: simultaneous multimodal neuroimaging approaches for exploring the organization of brain networks.Neurophotonics · 2022Review
- Existing function in primary visual cortex is not perturbed by new skill acquisition of a non-matched sensory task.Nature communications · 2022Article
- The diversity and specificity of functional connectivity across spatial and temporal scales.NeuroImage · 2021Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Intentional control over external objects is informed by our sensory experience of them. To study how causal relationships are learned and effected, we devised a brain machine interface (BMI) task using wide-field calcium signals. Mice learned to entrain activity patterns in arbitrary pairs of cortical regions to guide a visual cursor to a target location for reward. Brain areas that were normally correlated could be rapidly reconfigured to exert control over the cursor in a sensory-feedback-dependent manner. Higher visual cortex was more engaged when expert but not naive animals controlled the cursor. Individual neurons in higher visual cortex responded more strongly to the cursor when mice controlled it than when they passively viewed it, with the greatest response boosting as the cursor approached the target location. Thus, representations of causally controlled objects are sensitive to intention and proximity to the subject's goal, potentially strengthening sensory feedback to allow more fluent control.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.