ArticleeLife2020
Constitutive activation of cellular immunity underlies the evolution of resistance to infection in
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 47 citations in OpenAlex.
- A hybrid transcriptome assembly reveals coding and noncoding landscapes in Drosophila hemocytes.Genetics · 2026Article
- mTOR signaling regulates demand-adapted hematopoiesis and metabolic reprogramming required for an effective cellular immune response in Drosophila melanogaster larvae.PLoS genetics · 2026Article
- Single-cell RNA analysis reveals unexpected hemocyte plasticity and immune cell specialization in abioRxiv : the preprint server for biology · 2026Article
- Niche-derived exosomes controlFrontiers in immunology · 2026Article
- Muscling in on immunity: the role of muscle in the insect immune response, demonstrating the value of a whole organism perspective.Frontiers in immunology · 2026Review
- Nymphal diets boost adults' immunity via strengthened constitutive immunity and metabolic capacity in Adelphocoris suturalis.Communications biology · 2025Article
- Priming for protection: inducible attachment-resistance to ectoparasitic mites inParasitology · 2025Article
- Dysregulated Pathways During Pregnancy Predict Drug Candidates in Neurodevelopmental Disorders.Neuroscience bulletin · 2025Article
- Evolution of resistance and disease tolerance mechanisms to oral bacterial infection inOpen biology · 2025Article
- Innate Immunity in Insects: The Lights and Shadows of Phenoloxidase System Activation.International journal of molecular sciences · 2025Review
- Inferring the energy cost of resistance to parasitic infection and its link to a trade-off.BMC ecology and evolution · 2025Article
- Multigenerational inheritance of parasitic stress memory inEnvironmental epigenetics · 2025Article
- Recognition of nonself is necessary to activate Drosophila's immune response against an insect parasite.BMC biology · 2024Article
- Tick hemocytes have a pleiotropic role in microbial infection and arthropod fitness.Nature communications · 2024Article
- The evolution of constitutively active humoral immune defenses in Drosophila populations under high parasite pressure.PLoS pathogens · 2024Article
- Review
- Molecular traces of Drosophila hemocytes reveal transcriptomic conservation with vertebrate myeloid cells.PLoS genetics · 2023Article
- Single-cell transcriptomics identifies new blood cell populations in Drosophila released at the onset of metamorphosis.Development (Cambridge, England) · 2023Article
- Single-cell sequencing of tumor-associated macrophages in aFrontiers in immunology · 2023Article
- Hallmarks of crustacean immune hemocytes at single-cell resolution.Frontiers in immunology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Organisms rely on inducible and constitutive immune defences to combat infection. Constitutive immunity enables a rapid response to infection but may carry a cost for uninfected individuals, leading to the prediction that it will be favoured when infection rates are high. When we exposed populations of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.